(Q38172901)

30 August 2017

Cellular evidence for selfish spermatogonial selection in aged human testes (English)

1 reference

Andrew Oliver Mungo Wilkie

30 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Geoffrey Maher

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Anne Goriely

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

G J Maher

1

1 reference

30 August 2017

19 December 2013

1 reference

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

304-314

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24357637%20AND%20SRC:MED&resulttype=core&format=json

Telomere length predicts replicative capacity of human fibroblasts

12 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Decline in semen quality among fertile men in Paris during the past 20 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Telomere instability in the male germline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Pattern of compartmentation in human seminiferous tubules showing dislocation of spermatogonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Accumulation of driver and passenger mutations during tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

A germ-line-selective advantage rather than an increased mutation rate can explain some unexpectedly common human disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Positive selection for new disease mutations in the human germline: evidence from the heritable cancer syndrome multiple endocrine neoplasia type 2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Age and sex effects on human mutation rates: an old problem with new complexities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Spermatogonial stem cells: mouse and human comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

21 January 2018

Spermatocytic seminoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

A revised model for spermatogonial expansion in man: lessons from non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

The association of age and semen quality in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Expression of FGFR3 during human testis development and in germ cell-derived tumours of young adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

PIK3CA-AKT pathway mutations in micropapillary breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Advanced paternal and grandpaternal age and schizophrenia: a three-generation perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

A matter of life and death: self-renewal in stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

"Selfish spermatogonial selection": a novel mechanism for the association between advanced paternal age and neurodevelopmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Risk of autism and increasing maternal and paternal age in a large north American population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Fibroblast growth factor receptor 2, gain-of-function mutations, and tumourigenesis: investigating a potential link.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Isolation, characterization, and culture of human spermatogonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Dislocated type-A spermatogonia in human seminiferous tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Rate of de novo mutations and the importance of father's age to disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Differential marker protein expression specifies rarefaction zone-containing human Adark spermatogonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Akt mediates self-renewal division of mouse spermatogonial stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Relationship between age and semen parameters in men with normal sperm concentration: analysis of 6022 semen samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Whole-genome sequencing in autism identifies hot spots for de novo germline mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

PIK3CA mutations in in situ and invasive breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Novel stage classification of human spermatogenesis based on acrosome development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

The spermatocytic seminoma: views on pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Receptor specificity of the fibroblast growth factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Ageing of the male germ line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

The molecular anatomy of spontaneous germline mutations in human testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Somatic gain-of-function mutations in PIK3CA in patients with macrodactyly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Response of the human testis to long-term estrogen treatment: morphology of Sertoli cells, Leydig cells and spermatogonial stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

New evidence for positive selection helps explain the paternal age effect observed in achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

The ups and downs of mutation frequencies during aging can account for the Apert syndrome paternal age effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Age-dependent germline mosaicism of the most common noonan syndrome mutation shows the signature of germline selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X

Parental age and risk of childhood cancers: a population-based cohort study from Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.2047-2927.2013.00175.X