(Q38178605)

30 August 2017

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title

Functional inactivation of genes by dominant negative mutations (English)

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30 August 2017

Herskowitz I

1

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PubMed ID

2442619

30 August 2017

language of work or name

English

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publication date

1 September 1987

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30 August 2017

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30 August 2017

329

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30 August 2017

219-222

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30 August 2017

6136

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https://scigraph.springernature.com/pub.10.1038/329219a0

30 August 2017

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cites work

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7 January 2021

Efficient isolation of genes by using antibody probes

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Replacement of chromosome segments with altered DNA sequences constructed in vitro

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[12] One-step gene disruption in yeast

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cdc25+ functions as an inducer in the mitotic control of fission yeast.

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Direct and indirect gene replacements in Aspergillus nidulans

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Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

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Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene.

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Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis

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Injected anti-sense RNAs specifically block messenger RNA translation in vivo

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Production of phenocopies by Krüppel antisense RNA injection into Drosophila embryos.

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Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells

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Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA.

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Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity.

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A developmentally regulated activity that unwinds RNA duplexes

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7 January 2021

Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission

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10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin

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A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. II. Effects on cell movement, organization of microtubules, and intermediate filaments, and arrangement of Golgi elements

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Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

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Reversal of transformed phenotype by monoclonal antibodies against Ha-ras p21 proteins.

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DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

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Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

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Mutational studies with the trp repressor of Escherichia coli support the helix-turn-helix model of repressor recognition of operator DNA.

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Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor

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Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

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Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

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HTLV x gene mutants exhibit novel transcriptional regulatory phenotypes.

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Dominant mutations affecting muscle structure in Caenorhabditis elegans that map near the actin gene cluster

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The DNA enzymology of protein machines

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Shared active sites in oligomeric enzymes: model studies with defective mutants of aspartate transcarbamoylase produced by site-directed mutagenesis

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Regeneration of active enzyme by formation of hybrids from inactive derivatives: implications for active sites shared between polypeptide chains of aspartate transcarbamoylase

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Quaternary constraint in hybrid of aspartate transcarbamylase containing wild-type and mutant catalytic subunits

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Novel subunit-subunit interactions in the structure of glutamine synthetase.

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Functional domains of the yeast regulatory protein GAL4.

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Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination.

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7 January 2021

Identifiers

DOI

10.1038/329219A0

1 reference

PubMed ID

2442619

Dimensions Publication ID

30 August 2017

0 references

1 reference

PubMed ID

2442619