(Q38180347)

30 August 2017

title

The roles of Pellino E3 ubiquitin ligases in immunity (English)

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30 August 2017

1

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30 August 2017

language of work or name

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21 January 2014

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Nature Reviews Immunology

30 August 2017

published in

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30 August 2017

volume

14

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30 August 2017

issue

2

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30 August 2017

page(s)

122-131

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The history of Toll-like receptors - redefining innate immunity.

30 August 2017

cites work

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NOD-like receptors: role in innate immunity and inflammatory disease

21 January 2018

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Immune signaling by RIG-I-like receptors

21 January 2018

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Immune sensing of DNA

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Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal

21 January 2018

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Pellino enhances innate immunity in Drosophila.

21 January 2018

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Cutting edge: mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling

21 January 2018

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Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex

21 January 2018

1 reference

Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein

21 January 2018

1 reference

21 January 2018

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Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping

21 January 2018

1 reference

Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases

21 January 2018

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Characterization of Pellino2, a substrate of IRAK1 and IRAK4

21 January 2018

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Pellino2 activates the mitogen activated protein kinase pathway

21 January 2018

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Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner

21 January 2018

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Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases

21 January 2018

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The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1.

21 January 2018

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Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1

21 January 2018

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Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4.

21 January 2018

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The role of TBK1 and IKKε in the expression and activation of Pellino 1.

21 January 2018

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Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD.

21 January 2018

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Pellino-1 selectively regulates epithelial cell responses to rhinovirus.

21 January 2018

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Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9.

21 January 2018

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Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.

21 January 2018

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Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-beta1-induced negative regulation of IL-1R/TLR signaling

21 January 2018

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Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control

21 January 2018

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Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

21 January 2018

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Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

21 January 2018

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

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Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

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Pellino1 is required for interferon production by viral double-stranded RNA.

21 January 2018

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DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.

21 January 2018

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Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

21 January 2018

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Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

21 January 2018

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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

21 January 2018

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BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2

21 January 2018

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Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation

21 January 2018

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Mal mediates TLR-induced activation of CREB and expression of IL-10.

21 January 2018

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Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons

21 January 2018

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TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1

21 January 2018

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OxLDL inhibits LPS-induced IFNβ expression by Pellino3- and IRAK1/4-dependent modification of TANK.

21 January 2018

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Proteomic and transcriptomic analyses of macrophages with an increased resistance to oxidized low density lipoprotein (oxLDL)-induced cytotoxicity generated by chronic exposure to oxLDL.

21 January 2018

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Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis

21 January 2018

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Nod-like receptors in the control of intestinal inflammation.

21 January 2018

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The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

21 January 2018

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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

21 January 2018

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Signalling pathways of the TNF superfamily: a double-edged sword

21 January 2018

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RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

21 January 2018

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A poxviral homolog of the Pellino protein inhibits Toll and Toll-like receptor signalling.

21 January 2018

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Toll-like receptors-related genes in kidney transplant patients with chronic allograft nephropathy and acute rejection.

21 January 2018

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Assessment of risk factors for Korean children with Kawasaki disease

21 January 2018

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A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease

21 January 2018

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Ubiquitin makes its mark on immune regulation

21 January 2018

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A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

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The role of ubiquitylation in immune defence and pathogen evasion

21 January 2018

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Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

31 March 2020

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Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples

31 March 2020

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Peli1 (rel)ieves autoimmunity

31 March 2020

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Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI3599

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30 August 2017

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