(Q38181331)

30 August 2017

title

Innate immunity to Toxoplasma gondii infection (English)

1 reference

30 August 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Felix Yarovinsky

series ordinal

1

1 reference

30 August 2017

publication date

1 February 2014

1 reference

Nature Reviews Immunology

30 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

109-121

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

Regulation of CD8+ T cell responses to infection with parasitic protozoa

2 June 2020

cites work

1 reference

Cytokine regulation of immunopathology in toxoplasmosis

31 March 2020

1 reference

T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii

31 March 2020

1 reference

Modulation of innate immunity by Toxoplasma gondii virulence effectors

31 March 2020

1 reference

Pattern recognition receptors and inflammation

31 March 2020

1 reference

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

31 March 2020

1 reference

Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.

31 March 2020

1 reference

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

31 March 2020

1 reference

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii

31 March 2020

1 reference

Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.

31 March 2020

1 reference

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

31 March 2020

1 reference

In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

31 March 2020

1 reference

Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response

31 March 2020

1 reference

Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors

31 March 2020

1 reference

Approaching the asymptote? Evolution and revolution in immunology

31 March 2020

1 reference

UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii

31 March 2020

1 reference

Innate responses to Toxoplasma gondii in mice and humans

31 March 2020

1 reference

Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin

31 March 2020

1 reference

Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii

31 March 2020

1 reference

Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

31 March 2020

1 reference

Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines

31 March 2020

1 reference

UNC93B1 mediates host resistance to infection with Toxoplasma gondii

31 March 2020

1 reference

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

31 March 2020

1 reference

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

31 March 2020

1 reference

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells

31 March 2020

1 reference

Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides

31 March 2020

1 reference

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

31 March 2020

1 reference

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

31 March 2020

1 reference

In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

31 March 2020

1 reference

A Toll-like receptor recognizes bacterial DNA

31 March 2020

1 reference

The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation

31 March 2020

1 reference

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

31 March 2020

1 reference

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

31 March 2020

1 reference

Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation

31 March 2020

1 reference

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

31 March 2020

1 reference

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

31 March 2020

1 reference

Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

31 March 2020

1 reference

Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger

31 March 2020

1 reference

Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

31 March 2020

1 reference

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity

31 March 2020

1 reference

Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors.

31 March 2020

1 reference

Early response of mucosal epithelial cells during Toxoplasma gondii infection

31 March 2020

1 reference

TLR2 as an essential molecule for protective immunity against Toxoplasma gondii infection

31 March 2020

1 reference

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

31 March 2020

1 reference

Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis

31 March 2020

1 reference

Immunological reactions in response to apicomplexan glycosylphosphatidylinositols

31 March 2020

1 reference

Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1

31 March 2020

1 reference

Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70.

31 March 2020

1 reference

NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells.

31 March 2020

1 reference

Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

31 March 2020

1 reference

IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

31 March 2020

1 reference

Interleukin-12 and the regulation of innate resistance and adaptive immunity

31 March 2020

1 reference

Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

31 March 2020

1 reference

CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites

31 March 2020

1 reference

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

31 March 2020

1 reference

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

31 March 2020

1 reference

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

31 March 2020

1 reference

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

31 March 2020

1 reference

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

31 March 2020

1 reference

Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells

31 March 2020

1 reference

Compensatory dendritic cell development mediated by BATF-IRF interactions

31 March 2020

1 reference

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3.

31 March 2020

1 reference

Regulation of adaptive immunity by the innate immune system

31 March 2020

1 reference

On regulation of phagosome maturation and antigen presentation

31 March 2020

1 reference

Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

31 March 2020

1 reference

TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity

31 March 2020

1 reference

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

31 March 2020

1 reference

TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite

31 March 2020

1 reference

Invasion and intracellular survival by protozoan parasites

31 March 2020

1 reference

Toxoplasma gondii resides in a vacuole that avoids fusion with host cell endocytic and exocytic vesicular trafficking pathways

31 March 2020

1 reference

Functional Inactivation of Immature Dendritic Cells by the Intracellular Parasite Toxoplasma gondii

31 March 2020

1 reference

Diverse mechanisms employed by Toxoplasma gondii to inhibit IFN-gamma-induced major histocompatibility complex class II gene expression

31 March 2020

1 reference

Dysregulation of macrophage signal transduction by Toxoplasma gondii: past progress and recent advances

31 March 2020

1 reference

Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii

31 March 2020

1 reference

Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells

31 March 2020

1 reference

Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells

31 March 2020

1 reference

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.

31 March 2020

1 reference

Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondii

31 March 2020

1 reference

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii

31 March 2020

1 reference

Toxoplasma co-opts host cells it does not invade

31 March 2020

1 reference

Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells

31 March 2020

1 reference

Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii

31 March 2020

1 reference

Toxoplasma gondii: evidence for interleukin-12-dependent and-independent pathways of interferon-gamma production induced by an attenuated parasite strain

31 March 2020

1 reference

TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens

31 March 2020

1 reference

Recognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathology

31 March 2020

1 reference

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

31 March 2020

1 reference

Characterization of an indoleamine 2,3-dioxygenase induced by gamma-interferon in cultured human fibroblasts

31 March 2020

1 reference

Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice

31 March 2020

1 reference

Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

31 March 2020

1 reference

Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection

31 March 2020

1 reference

Antimicrobial reactive oxygen and nitrogen species: concepts and controversies

31 March 2020

1 reference

Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation

31 March 2020

1 reference

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

31 March 2020

1 reference

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

31 March 2020

1 reference

Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii

31 March 2020

1 reference

Induction of tumor necrosis factor-alpha and inducible nitric oxide synthase fails to prevent toxoplasmic encephalitis in the absence of interferon-gamma in genetically resistant BALB/c mice

31 March 2020

1 reference

L-arginine-dependent reactive nitrogen intermediates and the antimicrobial effect of activated human mononuclear phagocytes

31 March 2020

1 reference

Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates

31 March 2020

1 reference

Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens

31 March 2020

1 reference

Macrophage oxidative metabolism and intracellular Toxoplasma gondii

31 March 2020

1 reference

p47 GTPases: regulators of immunity to intracellular pathogens

31 March 2020

1 reference

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

31 March 2020

1 reference

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

31 March 2020

1 reference

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

31 March 2020

1 reference

The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens

31 March 2020

1 reference

Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

31 March 2020

1 reference

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

31 March 2020

1 reference

p47 GTPases regulate Toxoplasma gondii survival in activated macrophages

31 March 2020

1 reference

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

31 March 2020

1 reference

Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

31 March 2020

1 reference

31 March 2020

1 reference

The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

31 March 2020

1 reference

Balance of Irgm protein activities determines IFN-gamma-induced host defense

31 March 2020

1 reference

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

31 March 2020

1 reference

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

31 March 2020

1 reference

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

31 March 2020

1 reference

The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?

31 March 2020

1 reference

Interferon-inducible immunity-related GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy

31 March 2020

1 reference

Regulation of macrophage motility by Irgm1

31 March 2020

1 reference

31 March 2020

1 reference

The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation

31 March 2020

1 reference

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii

31 March 2020

1 reference

ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

31 March 2020

1 reference

The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18

31 March 2020

1 reference

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii

31 March 2020

1 reference

Human IRGM gene “to be or not to be”

31 March 2020

1 reference

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

31 March 2020

1 reference

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense

31 March 2020

1 reference

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies

31 March 2020

1 reference

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

31 March 2020

1 reference

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication

31 March 2020

1 reference

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins

31 March 2020

1 reference

The evolution of vertebrate Toll-like receptors

31 March 2020

1 reference

Toxoplasma gondii effectors are master regulators of the inflammatory response

31 March 2020

1 reference

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

31 March 2020

1 reference

12 December 2020

Interleukin-12 enhances murine survival against acute toxoplasmosis

1 reference

12 December 2020

Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma

1 reference

12 December 2020

Role of TNF and IL-1 in infections with Toxoplasma gondii

1 reference

12 December 2020

Crucial role of TNF receptor type 1 (p55), but not of TNF receptor type 2 (p75), in murine toxoplasmosis

1 reference

12 December 2020

Studies on the role of interleukin-12 in acute murine toxoplasmosis

1 reference

12 December 2020

Inducible nitric oxide synthase is not required for long-term vaccine-based immunity against Toxoplasma gondii

1 reference

12 December 2020

NLRP1 is an inflammasome sensor for Toxoplasma gondii

1 reference

12 December 2020

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1 reference

12 December 2020

TLR9 is important for protection against intestinal damage and for intestinal repair

1 reference

12 December 2020

Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha

1 reference

12 December 2020

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

1 reference

12 December 2020

Inhibition of inducible nitric oxide synthase exacerbates chronic cerebral toxoplasmosis in Toxoplasma gondii-susceptible C57BL/6 mice but does not reactivate the latent disease in T. gondii-resistant BALB/c mice.

1 reference

12 December 2020

CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin.

1 reference

12 December 2020

Decreased resistance of TNF receptor p55- and p75-deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivo

1 reference

12 December 2020

Tumor necrosis factor-alpha triggers antitoxoplasmal activity of IFN-gamma primed macrophages

1 reference

12 December 2020

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

12 December 2020

Association of host cell endoplasmic reticulum and mitochondria with the Toxoplasma gondii parasitophorous vacuole membrane: a high affinity interaction

1 reference

12 December 2020

Intracellular fate of vacuoles containing Toxoplasma gondii is determined at the time of formation and depends on the mechanism of entry

1 reference

12 December 2020

Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.

1 reference

12 December 2020

IL-1 beta is required for IL-12 to induce production of IFN-gamma by NK cells. A role for IL-1 beta in the T cell-independent mechanism of resistance against intracellular pathogens

1 reference

12 December 2020

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI3598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24457485%20AND%20SRC:MED&resulttype=core&format=json

release_vt3nf7ld2zhnzfu52hdtgasafu

2 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/vt3nf7ld2zhnzfu52hdtgasafu

24 November 2022

mapped directly with Wikidata item

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