(Q38211812)

31 August 2017

title

Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease--a comprehensive review (English)

1 reference

31 August 2017

0 references

ascending cholangitis

0 references

sclerosing cholangitis

1 reference

primary sclerosing cholangitis

inferred from title

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Stan F van de Graaf

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Simon Hohenester

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Ronald P J Oude Elferink

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Ulrich Beuers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

publication date

1 June 2015

1 reference

Clinical Reviews in Allergy & Immunology

31 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

2-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

182-191

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24828903%20AND%20SRC:MED&resulttype=core&format=json

Divergent evolution of fucosyltransferase genes from vertebrates, invertebrates, and bacteria

3 June 2020

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Molecular cloning of a human genomic region containing the H blood group alpha(1,2)fucosyltransferase gene and two H locus-related DNA restriction fragments. Isolation of a candidate for the human Secretor blood group locus

21 January 2018

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21 January 2018

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The metabolism of L-fucose by HeLa cells

21 January 2018

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Glycoprotein lysosomal storage disorders: alpha- and beta-mannosidosis, fucosidosis and alpha-N-acetylgalactosaminidase deficiency

21 January 2018

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Equilibration of fucosyl glycoprotein pools in HeLa cells

21 January 2018

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Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen

21 January 2018

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Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype

21 January 2018

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The ABO blood group antigens and their secretion by healthy and diseased gastric mucosa

21 January 2018

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The blood group-specific human glycosyltransferases

21 January 2018

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Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa

21 January 2018

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Molecular basis for erythrocyte Le(a+ b+) and salivary ABH partial-secretor phenotypes: expression of a FUT2 secretor allele with an A-->T mutation at nucleotide 385 correlates with reduced alpha(1,2) fucosyltransferase activity

21 January 2018

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Correlation of a missense mutation in the human Secretor alpha 1,2-fucosyltransferase gene with the Lewis(a+b+) phenotype: a potential molecular basis for the weak Secretor allele (Sew).

21 January 2018

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Genetic variation of FUT2 in a Ghanaian population: identification of four novel mutations and inference of balancing selection.

21 January 2018

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Searching for signals of evolutionary selection in 168 genes related to immune function.

21 January 2018

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A natural history of FUT2 polymorphism in humans.

21 January 2018

1 reference

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A homozygous nonsense mutation (428G-->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections

21 January 2018

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Common variants of FUT2 are associated with plasma vitamin B12 levels

21 January 2018

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Unravelling the pathogenesis of inflammatory bowel disease

21 January 2018

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Inflammatory Bowel Disease

21 January 2018

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Promises, delivery, and challenges of inflammatory bowel disease risk gene discovery

21 January 2018

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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

1 reference

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Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Two new FUT2 (fucosyltransferase 2 gene) missense polymorphisms, 739G-->A and 839T-->C, are partly responsible for non-secretor status in a Caucasian population from Northern Portugal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease

21 January 2018

1 reference

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Lack of common NOD2 variants in Japanese patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Role of commensal gut bacteria in inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens

21 January 2018

1 reference

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Glycans as legislators of host-microbial interactions: spanning the spectrum from symbiosis to pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

A DNA polymorphism influencing alpha(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

A model of host-microbial interactions in an open mammalian ecosystem

21 January 2018

1 reference

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Glucocorticoids and microbiota regulate ontogeny of intestinal fucosyltransferase 2 requisite for gut homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

21 January 2018

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Association of fucosyltransferase 2 gene variants with ulcerative colitis in Han and Uyghur patients in China

21 January 2018

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Inflammatory bowel disease: etiology and pathogenesis

21 January 2018

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Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management

21 January 2018

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Genome-wide association analysis in primary sclerosing cholangitis

21 January 2018

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Primary sclerosing cholangitis

21 January 2018

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Role of the microbiota and antibiotics in primary sclerosing cholangitis

21 January 2018

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Intestinal permeability and bacterial growth of the small bowel in patients with primary sclerosing cholangitis

21 January 2018

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The role of dominant stenoses in bacterial infections of bile ducts in primary sclerosing cholangitis

21 January 2018

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Etiopathogenesis of primary sclerosing cholangitis

21 January 2018

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The dynamic biliary epithelia: molecules, pathways, and disease

21 January 2018

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Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

21 January 2018

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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

21 January 2018

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Evaluation of abnormal liver-enzyme results in asymptomatic patients

21 January 2018

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Diagnosis and management of primary sclerosing cholangitis.

21 January 2018

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The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies

21 January 2018

1 reference

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A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes.

21 January 2018

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Decrease of sialic acid residues as an eat-me signal on the surface of apoptotic lymphocytes.

21 January 2018

1 reference

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Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrin-mediated migration of human melanoma cells.

21 January 2018

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pH nanoenvironment at the surface of single melanoma cells

21 January 2018

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Infection by Helicobacter pylori expressing the BabA adhesin is influenced by the secretor phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Expression of Lewis antigens and their precursors in gastric mucosa: relationship with Helicobacter pylori infection and gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Influence of the ABO blood groups and secretor status on bleeding and on perforation of duodenal ulcer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Host genetic resistance to symptomatic norovirus (GGII.4) infections in Denmark

21 January 2018

1 reference

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Epidemiology of Norwalk Gastroenteritis and the Role of Norwalk Virus in Outbreaks of Acute Nonbacterial Gastroenteritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns

21 January 2018

1 reference

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Antibody prevalence and titer to norovirus (genogroup II) correlate with secretor (FUT2) but not with ABO phenotype or Lewis (FUT3) genotype.

21 January 2018

1 reference

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Virus serology in familial Crohn disease.

21 January 2018

1 reference

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A FUT2 gene common polymorphism determines resistance to rotavirus A of the P[8] genotype

21 January 2018

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Pathogenesis of urinary tract infections: an update

21 January 2018

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Non-secretion of ABO blood group antigens predisposing to infection by Haemophilus influenzae

21 January 2018

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Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae

21 January 2018

1 reference

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Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Vitamin B12 sources and bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G->A) and vitamin B-12 in Europe and West Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Gastric intrinsic factor deficiency with combined GIF heterozygous mutations and FUT2 secretor variant.

21 January 2018

1 reference

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A large-scale screen for coding variants predisposing to psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Human metabolic individuality in biomedical and pharmaceutical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Regulation of the oncodevelopmental expression of type 1 chain ABH and Lewis(b) blood group antigens in human colon by alpha-2-L-fucosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Aberrant alpha 1-->2fucosyltransferases found in human colorectal carcinoma involved in the accumulation of Leb and Y antigens in colorectal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Polymorphisms of Lewis and Secretor genes are related to breast cancer and metastasis in axillary lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

21 January 2018

1 reference

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Lack of association of non-synonymous FUT2 and ALPL polymorphisms with venous thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Bile duct bacterial isolates in primary sclerosing cholangitis: a study of explanted livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-014-8423-1

Molecular basis for secretor type alpha(1,2)-fucosyltransferase gene deficiency in a Japanese population: a fusion gene generated by unequal crossover responsible for the enzyme deficiency

21 January 2018

1 reference

12 December 2020

Lewis and secretor gene dosages affect CA19-9 and DU-PAN-2 serum levels in normal individuals and colorectal cancer patients

1 reference

12 December 2020

Gut microbiota: FUT2 genotype influences the gut microbiota in patients with Crohn's disease and healthy individuals

1 reference

12 December 2020

FUT2: filling the gap between genes and environment in Behçet's disease?

1 reference

12 December 2020

ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women.

1 reference

12 December 2020

Non-secretion of blood group antigens and susceptibility to infection by Candida species

1 reference

12 December 2020

Secretor genotyping for A385T, G428A, C571T, C628T, 685delTGG, G849A, and other mutations from a single PCR

1 reference

12 December 2020

The polymorphisms of fucosyltransferases

1 reference

12 December 2020

L-fucose is accumulated via a specific transport system in eukaryotic cells.

1 reference

12 December 2020

Association of recurrent vaginal candidiasis and secretory ABO and Lewis phenotype

1 reference

12 December 2020

Non-secretor status is associated with female acute uncomplicated pyelonephritis

1 reference

12 December 2020

Association study ofFUT2(rs601338) with celiac disease and inflammatory bowel disease in the Finnish population

1 reference

12 December 2020

Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody.

1 reference

12 December 2020

Purification of H gene-encoded beta-galactoside alpha 1----2 fucosyltransferase from human serum

1 reference

12 December 2020

Oral Candida carriage and blood group antigen secretor status

1 reference

12 December 2020

Decoding norovirus infection in Crohn's disease

1 reference

12 December 2020

Human erythrocyte antigen expression: its molecular bases

1 reference

12 December 2020

Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing fucosyl or sialyl-fucosyl type 2 chain polylactosamine

1 reference

12 December 2020

A new genetic model proposing that the Se gene is a structural gene closely linked to the H gene

1 reference

12 December 2020

Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men

1 reference

12 December 2020

Increased prevalence of primary sclerosing cholangitis among first-degree relatives

1 reference

12 December 2020

Evidence that the enzyme catalyzing the conversion of guanosine diphosphate D-mannose to a 4-keto sugar nucleotide intermediate requires nicotinamide adenine dinucleotide phosphate

1 reference

12 December 2020

Purification of the blood group H gene associated alpha-2-L-fucosyltransferase from human plasma

1 reference

12 December 2020

The role of indigenous microflora in the development of murine intestinal fucosyl- and sialyltransferases

1 reference

12 December 2020