(Q38227144)

31 August 2017

title

CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance (English)

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31 August 2017

1 reference

Lars Nitschke

1

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31 August 2017

publication date

6 July 2014

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31 August 2017

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31 August 2017

volume

24

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31 August 2017

issue

9

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31 August 2017

page(s)

807-817

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CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold

31 August 2017

cites work

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21 January 2018

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Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12.

21 January 2018

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Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

21 January 2018

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Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.

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Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.

21 January 2018

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B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase

21 January 2018

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Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction.

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

In vivo targeting of B-cell lymphoma with glycan ligands of CD22.

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Siglecs and their roles in the immune system

21 January 2018

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Genetic susceptibility to SLE: recent progress from GWAS.

21 January 2018

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Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation

21 January 2018

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Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation

21 January 2018

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A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP

21 January 2018

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Role of B-1a cells in autoimmunity

21 January 2018

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Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

21 January 2018

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Identification of the ligand-binding domains of CD22, a member of the immunoglobulin superfamily that uniquely binds a sialic acid-dependent ligand

21 January 2018

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B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling

21 January 2018

1 reference

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Regulation of B cell development and B cell signalling by CD22 and its ligands alpha2,6-linked sialic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking

21 January 2018

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Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

21 January 2018

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Immune regulation by the ST6Gal sialyltransferase

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 regulates adaptive and innate immune responses of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Mouse beta-galactoside alpha 2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Efficient killing of CD22+ tumor cells by a humanized diabody-RNase fusion protein

21 January 2018

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Polymorphisms in the Cd22 gene of inbred mouse strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Preclinical and clinical evaluation of epratuzumab (anti-CD22 IgG) in B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 is required for protection against West Nile virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22a lupus-prone mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Suppressing the antibody response with Siglec ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 is a negative regulator of B-cell receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Hyperresponsive B cells in CD22-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 regulates time course of both B cell division and antibody response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 regulates thymus-independent responses and the lifespan of B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Regulation of CD45 engagement by the B-cell receptor CD22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

CD22 ligation inhibits downstream B cell receptor signaling and Ca(2+) flux upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Inhibition of the B cell by CD22: a requirement for Lyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Characterization of mouse sialyltransferase genes: their evolution and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Predominant autoantibody production by early human B cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

Cell surface sialic acids do not affect primary CD22 interactions with CD45 and surface IgM nor the rate of constitutive CD22 endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWU066

21 January 2018

Identifiers

DOI

10.1093/GLYCOB/CWU066

1 reference

31 August 2017

1 reference