(Q38227267)

31 August 2017

title

Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease (English)

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31 August 2017

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J Charles Jennette

1

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31 August 2017

Ronald J Falk

series ordinal

2

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31 August 2017

language of work or name

English

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publication date

8 July 2014

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Nature Reviews Rheumatology

31 August 2017

published in

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31 August 2017

volume

10

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31 August 2017

issue

8

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31 August 2017

page(s)

463-473

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2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

31 August 2017

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Asymptomatic autoantibodies associate with future anti-glomerular basement membrane disease

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Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

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Relation between asymptomatic proteinase 3 antibodies and future granulomatosis with polyangiitis

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Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology?

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Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3.

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New insights that link microbes with the generation of antineutrophil cytoplasmic autoantibodies: the theory of autoantigen complementarity

21 January 2018

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Specific interactions between sense and complementary peptides: the basis for the proteomic code

21 January 2018

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ANCA patients have T cells responsive to complementary PR-3 antigen

21 January 2018

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DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans

21 January 2018

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Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis

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Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis

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Apoptosis-induced proteinase 3 membrane expression is independent from degranulation

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Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis

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Decreased numbers of blood dendritic cells and defective function of regulatory T cells in antineutrophil cytoplasmic antibody-associated vasculitis

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Patients with antineutrophil cytoplasmic antibody-associated vasculitis have defective Treg cell function exacerbated by the presence of a suppression-resistant effector cell population.

21 January 2018

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Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis.

21 January 2018

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Decreased CD5⁺ B cells in active ANCA vasculitis and relapse after rituximab.

21 January 2018

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Regulatory B cells in ANCA-associated vasculitis.

21 January 2018

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Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils

21 January 2018

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Plasma levels of soluble interleukin 2 receptor, soluble CD30, interleukin 10 and B cell activator of the tumour necrosis factor family during follow-up in vasculitis associated with proteinase 3-antineutrophil cytoplasmic antibodies: associations w

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B-lymphocyte activating factor levels are increased in patients with Wegener's granulomatosis and inversely correlated with ANCA titer.

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Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro

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Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha

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C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis

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Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG.

21 January 2018

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p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activation

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Antimyeloperoxidase Antibodies Induce Neutrophil Adherence to Cultured Human Endothelial Cells

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Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors

21 January 2018

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Monocyte activation in patients with Wegener's granulomatosis

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The role of myeloperoxidase and myeloperoxidase-antineutrophil cytoplasmic antibodies (MPO-ANCAs) in the pathogenesis of human MPO-ANCA-associated glomerulonephritis

21 January 2018

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Experimental models of vasculitis and glomerulonephritis induced by antineutrophil cytoplasmic autoantibodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Pathogenesis of ANCA-associated vasculitis: recent insights from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Animal models of antineutrophil cytoplasm antibody-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

C5a receptor (CD88) blockade protects against MPO-ANCA GN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The role of the innate immune system in granulomatous disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Is PR3-ANCA formation initiated in Wegener's granulomatosis lesions? Granulomas as potential lymphoid tissue maintaining autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Serum anti-lysosomal-associated membrane protein-2 antibody levels in cutaneous polyarteritis nodosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Colocalization of ANCA-antigens and fibrinoid necrosis in ANCA-associated vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

On the specific mutual interaction of amino acid residues of polypeptide chains and amino acid residues with codons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Idiotypic induction of autoimmunity: a new aspect of the idiotypic network.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Patients with Wegener's granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

BAFF is elevated in serum of patients with Wegener's granulomatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Serum levels of BAFF and APRIL in myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis: association with disease activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Myeloperoxidase binds to vascular endothelial cells, is recognized by ANCA and can enhance complement dependent cytotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Bone marrow-derived cells are sufficient and necessary targets to mediate glomerulonephritis and vasculitis induced by anti-myeloperoxidase antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils

31 March 2020

1 reference

12 December 2020

Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3.

1 reference

12 December 2020

Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils

1 reference

12 December 2020

Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.

1 reference

12 December 2020

Antibodies to neutrophil cytoplasmic antigens induce monocyte chemoattractant protein-1 secretion from human monocytes

1 reference

12 December 2020

Cross-linking of Fc gamma receptor IIa and Fc gamma receptor IIIb induces different proadhesive phenotypes on human neutrophils

1 reference

12 December 2020

Allergic granulomatosis, allergic angiitis, and periarteritis nodosa

1 reference

12 December 2020

Prominence of cell-mediated immunity effectors in "pauci-immune" glomerulonephritis

1 reference

12 December 2020

Glomerular monocyte-macrophage features in ANCA-positive renal vasculitis and cryoglobulinemic nephritis

1 reference

12 December 2020

Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase

1 reference

12 December 2020

Antibodies against granule proteins activate neutrophils in vitro

1 reference

12 December 2020

Presence of neutrophil extracellular traps and antineutrophil cytoplasmic antibodies associated with vasculitides

1 reference

12 December 2020

Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies.

1 reference

12 December 2020

Antineutrophil cytoplasmic antibodies (ANCAs) in patients with inflammatory bowel disease show no correlation with proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G and lysozyme: a Singapore study

1 reference

12 December 2020

Current knowledge on cellular interactions in the WG-granuloma.

1 reference

12 December 2020

Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2014.103

1 reference

Dimensions Publication ID

31 August 2017

1002120822

0 references

1 reference