(Q38233673)

31 August 2017

A potential role for mechanical forces in the detachment of podocytes and the progression of CKD. (English)

1 reference

31 August 2017

Wilhelm Kriz

1

1 reference

PMCID

4310663

31 August 2017

Kevin V Lemley

series ordinal

2

1 reference

31 August 2017

24 July 2014

1 reference

Journal of the American Society of Nephrology

31 August 2017

1 reference

31 August 2017

26

1 reference

31 August 2017

2

1 reference

31 August 2017

258-269

1 reference

Fluid flow shear stress over podocytes is increased in the solitary kidney

31 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Urine podocyte mRNAs, proteinuria, and progression in human glomerular diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

5/6th nephrectomy in combination with high salt diet and nitric oxide synthase inhibition to induce chronic kidney disease in the Lewis rat

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyturia predates proteinuria and clinical features of preeclampsia: longitudinal prospective study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The podocyte's response to stress: the enigma of foot process effacement

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte mitosis - a catastrophe.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The challenge and response of podocytes to glomerular hypertension

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Growth-dependent podocyte failure causes glomerulosclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Development of structural kidney damage in spontaneously hypertensive rats.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

CONTRACTILITY OF THE RENAL GLOMERULUS AND MESANGIAL CELLS: LINGERING DOUBTS AND STRATEGIES FOR THE FUTURE.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Slit diaphragms contain tight junction proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Properties of the glomerular barrier and mechanisms of proteinuria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Renal function during normal pregnancy and preeclampsia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The slit diaphragm: a signaling platform to regulate podocyte function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Signaling at the slit diaphragm

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Urinary excretion of viable podocytes in health and renal disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Angiotensin II as a renal growth factor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte loss and progression of diabetic nephropathy.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Hypertrophy and hyperfunction of the diabetic kidney

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte loss and progressive glomerular injury in type II diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Anti-glomerular basement membrane glomerulonephritis (anti-GBM GN) in the mouse: BrdU-labelling indices and histological damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Structural basis for reduced glomerular filtration capacity in nephrotic humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular permeability. Ultrastructural studies in experimental nephrosis using horseradish peroxidase as a tracer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular epithelial abnormalities associated with the onset of proteinuria in aminonucleoside nephrosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular hypertrophy in minimal change disease predicts subsequent progression to focal glomerular sclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The altered glomerular filtration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Pathogenesis of polycation-induced alterations ("fusion") of glomerular epithelium

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Polycation-induced dislocation of slit diaphragms and formation of cell junctions in rat kidney glomeruli: the effects of low temperature, divalent cations, colchicine, and cytochalasin B

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocytes are sensitive to fluid shear stress in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Nephron adaptation to renal injury or ablation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Complement-mediated injury reversibly disrupts glomerular epithelial cell actin microfilaments and focal adhesions.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The hyperfiltration theory: a paradigm shift in nephrology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The role of podocytes in the development of glomerular sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular basement membrane as a compressible ultrafilter

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Mechanisms of progressive glomerular injury in membranous nephropathy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte detachment and epithelial cell reaction in focal segmental glomerulosclerosis with cellular variants.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

The renal hemodynamic basis of diabetic nephropathy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Explaining glomerular pores with fiber matrices. A visualization study based on computer modeling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Structural determinants of glomerular hydraulic permeability.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Ultrastructural changes in glomerular epithelial cells in acute puromycin aminonucleoside nephrosis: a study by high-resolution scanning electron microscopy

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocytic degeneration and regeneration in puromycin aminonucleoside nephropathy in the rat.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Compensatory adaptation of structure and function following progressive renal ablation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

An ultrastructural study of the mechanisms of proteinuria in aminonucleoside nephrosis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular hyperfiltration: definitions, mechanisms and clinical implications.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Protecting podocytes: how good do we need to be?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular filtration into the subpodocyte space is highly restricted under physiological perfusion conditions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Cell cycle regulatory proteins in podocyte health and disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Structure-stabilizing forces in the glomerular tuft.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Glomerular hypertrophy and epithelial cell injury modulate progressive glomerulosclerosis in the rat.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310663

Renoprotection by continuous erythropoietin receptor activator in puromycin aminonucleoside-induced nephrotic syndrome

31 August 2018

1 reference

12 December 2020

Glomerular podocyte vacuolation in focal segmental glomerulosclerosis

1 reference

12 December 2020

Altered glomerular permeability as a result of focal detachment of the visceral epithelium

1 reference

12 December 2020

Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis

1 reference

12 December 2020

Morphometry of the renal corpuscle during postnatal growth and compensatory hypertrophy

1 reference

12 December 2020

Glomerular damage after uninephrectomy in young rats. II. Mechanical stress on podocytes as a pathway to sclerosis

1 reference

12 December 2020

Glomerular podocyte vacuolation in idiopathic membranous glomerulonephritis

1 reference

12 December 2020

A role for podocytes to counteract capillary wall distension

1 reference

12 December 2020

Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis

1 reference

12 December 2020

Changes in glomerular structure following acute mesangial failure in the isolated perfused kidney

1 reference

12 December 2020

Altered glomerular permselectivity and progressive sclerosis following extreme ablation of renal mass

1 reference

12 December 2020

Dynamics of glomerular ultrafiltration in the rat. VII. Response to reduced renal mass

1 reference

12 December 2020

Glomerular damage after uninephrectomy in young rats. I. Hypertrophy and distortion of capillary architecture

1 reference

12 December 2020

Observations of glomerular epithelial cell structure in patients with type I diabetes mellitus

1 reference

12 December 2020

Canonical transient receptor potential 1 channel is involved in contractile function of glomerular mesangial cells

1 reference

12 December 2020

Intercellular junctions in podocytes of the nephrotic glomerulus as seen with freeze-fracture

1 reference

12 December 2020

Podocyte damage is a critical step in the development of glomerulosclerosis in the uninephrectomised-desoxycorticosterone hypertensive rat

1 reference

12 December 2020

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1 reference

12 December 2020

Focal glomerular sclerosis in nephrotic patients: An electron microscopic study of glomerular podocytes

1 reference

12 December 2020

Blood flow in the renal glomerulus

1 reference

12 December 2020

Glomerular epithelial detachment, not reduced charge density, correlates with proteinuria in adriamycin and puromycin nephrosis

1 reference

12 December 2020

Podocyte bridges between the tuft and Bowman's capsule: an early event in experimental crescentic glomerulonephritis

1 reference

12 December 2020

Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment

1 reference

12 December 2020

Three-dimensional reconstruction of glomeruli by electron microscopy reveals a distinct restrictive urinary subpodocyte space

1 reference

12 December 2020

Reversing glomerular hypertension stabilizes established glomerular injury

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2014030278

1 reference

31 August 2017

1 reference

31 August 2017

1 reference

PMCID

4310663