(Q38239639)

31 August 2017

Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome (English)

1 reference

acute respiratory distress syndrome

31 August 2017

1 reference

Naoki Aikawa

1

1 reference

PMCID

4130327

31 August 2017

Yasushi Kawasaki

series ordinal

2

1 reference

31 August 2017

5 August 2014

1 reference

Therapeutics and Clinical Risk Management

31 August 2017

1 reference

31 August 2017

10

1 reference

31 August 2017

621-629

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

31 August 2017

start time

1 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Pharmacological therapies for acute respiratory distress syndrome

1 reference

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Prone positioning in severe acute respiratory distress syndrome

6 September 2017

1 reference

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Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neutrophil elastase-mediated lung disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Clinical evaluation of sivelestat for acute lung injury/acute respiratory distress syndrome following surgery for abdominal sepsis

6 September 2017

1 reference

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Acute respiratory distress syndrome: the Berlin Definition

6 September 2017

1 reference

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Effect of neutrophil elastase inhibitor (sivelestat sodium) in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): a systematic review and meta-analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neuromuscular blockers in early acute respiratory distress syndrome

6 September 2017

1 reference

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6 September 2017

Steroids in early ARDS?

1 reference

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Acute lung injury and the acute respiratory distress syndrome: a clinical review

6 September 2017

1 reference

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Epidemiology and outcomes of acute lung injury.

6 September 2017

1 reference

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The role of neutrophil elastase in acute lung injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Pulmonary pathology of acute respiratory distress syndrome

6 September 2017

1 reference

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The acute respiratory distress syndrome

6 September 2017

1 reference

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Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

6 September 2017

1 reference

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The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination

6 September 2017

1 reference

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Tissue destruction by neutrophils

6 September 2017

1 reference

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Human plasma proteinase inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

28 September 2017

Steroids in late ARDS?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Release of interleukin-8, interleukin-6, and colony-stimulating factors by upper airway epithelial cells: implications for cystic fibrosis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Acute lung injury during cardiopulmonary bypass. Are the neutrophils responsible?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Sivelestat (selective neutrophil elastase inhibitor) improves the mortality rate of sepsis associated with both acute respiratory distress syndrome and disseminated intravascular coagulation patients.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neutrophil elastase inhibitor improves postoperative clinical courses after thoracic esophagectomy

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Relationship between neutrophil elastase and acute lung injury in humans

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Elastase inhibition reduced death associated with acid aspiration-induced lung injury in hamsters

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Pharmacological profile of a specific neutrophil elastase inhibitor, Sivelestat sodium hydrate

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Inhibition of neutrophil elastase activity attenuates complement-mediated lung injury in the hamster

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130327

[Clinical practice guideline for acute lung injury and acute respiratory distress syndrome]

31 August 2018

1 reference

12 December 2020

Microvascular permeability of the non-heart-beating rabbit lung after warm ischemia and reperfusion: role of neutrophil elastase

1 reference

12 December 2020

Neutrophil elastase-releasing factors in bronchoalveolar lavage from patients with adult respiratory distress syndrome

1 reference

12 December 2020

Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

1 reference

12 December 2020

Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study

1 reference

12 December 2020

Early administration of sivelestat, the neutrophil elastase inhibitor, in adults for acute lung injury following gastric aspiration

1 reference

12 December 2020

Effects of a neutrophil elastase inhibitor (ONO-5046) on acute pulmonary injury induced by tumor necrosis factor alpha (TNFalpha) and activated neutrophils in isolated perfused rabbit lungs

1 reference

12 December 2020

Physiology and Pathophysiology of Neutral Proteinases of Human Granulocytes

1 reference

12 December 2020

Delayed neutrophil elastase inhibition prevents subsequent progression of acute lung injury induced by endotoxin inhalation in hamsters

1 reference

12 December 2020

Diagnostic criteria for adult respiratory distress syndrome: time for reappraisal

1 reference

12 December 2020

Plasma elastase levels and the development of the adult respiratory distress syndrome

1 reference

12 December 2020

Identifiers

DOI

10.2147/TCRM.S65066

1 reference

31 August 2017

1 reference

31 August 2017

1 reference

PMCID

4130327