(Q38262258)

1 September 2017

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title

Development of a new tuberculosis vaccine: is there value in the mucosal approach? (English)

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1 September 2017

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Gil Reynolds Diogo

1

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1 September 2017

Rajko Reljic

series ordinal

2

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1 September 2017

publication date

1 January 2014

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1 September 2017

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1 September 2017

volume

6

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1 September 2017

issue

9

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1 September 2017

page(s)

1001-1013

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Update on research and development pipeline: tuberculosis vaccines

1 September 2017

cites work

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TB vaccines: current status and future perspectives

21 January 2018

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Nanotechnology solutions for mucosal immunization

21 January 2018

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New vaccines for tuberculosis

21 January 2018

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Mucosal vaccines: the promise and the challenge

21 January 2018

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Roles of Mucosal Immunity against Mycobacterium tuberculosis Infection

21 January 2018

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Mucosal vaccines: where do we stand?

21 January 2018

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21 January 2018

Mucosal immunoglobulins

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21 January 2018

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Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

21 January 2018

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Innate immune recognition of Mycobacterium tuberculosis

21 January 2018

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Host innate immune response to Mycobacterium tuberculosis

21 January 2018

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Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

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Innate immunity in tuberculosis: myths and truth.

21 January 2018

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

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Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis

21 January 2018

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Therapeutic potential of oral tolerance

21 January 2018

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Antigen presentation to naive CD4 T cells in the lymph node.

21 January 2018

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Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract

21 January 2018

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Fate of Mycobacterium tuberculosis within murine dendritic cells

21 January 2018

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Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis

21 January 2018

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Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response

21 January 2018

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NALT- versus Peyer's-patch-mediated mucosal immunity

21 January 2018

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Regional specialization in the mucosal immune system: primed cells do not always home along the same track

21 January 2018

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Mucosal immunity: some historical perspective on host-pathogen interactions and implications for mucosal vaccines.

21 January 2018

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Epithelial M cells: differentiation and function

21 January 2018

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The airway antigen sampling system: respiratory M cells as an alternative gateway for inhaled antigens.

21 January 2018

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Innate immunity to Mycobacterium tuberculosis

21 January 2018

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Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection

21 January 2018

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Does antibody to mycobacterial antigens, including lipoarabinomannan, limit dissemination in childhood tuberculosis?

21 January 2018

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Role of IgA in the defense against respiratory infections IgA deficient mice exhibited increased susceptibility to intranasal infection with Mycobacterium bovis BCG.

21 January 2018

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Intracellular neutralization of virus by immunoglobulin A antibodies

21 January 2018

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Intestinal IgA: novel views on its function in the defence of the largest mucosal surface.

21 January 2018

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Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

21 January 2018

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A novel human IgA monoclonal antibody protects against tuberculosis

21 January 2018

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Mucosal immunotherapy of tuberculosis: is there a value in passive IgA?

21 January 2018

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Tuberculosis control in the era of HIV.

21 January 2018

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Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs

21 January 2018

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ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

21 January 2018

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Activation of NKT cells protects mice from tuberculosis.

21 January 2018

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The host immune response to tuberculosis

21 January 2018

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Mucosal immunity and vaccines

21 January 2018

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Vaccination strategies for mucosal immune responses

21 January 2018

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Efficient induction of mucosal and systemic immune responses by virus-like particles administered intranasally: implications for vaccine design

21 January 2018

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Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza

21 January 2018

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Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

21 January 2018

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The immune geography of IgA induction and function

21 January 2018

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Immunization without needles

21 January 2018

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A recombinant attenuated Mycobacterium tuberculosis vaccine strain is safe in immunosuppressed simian immunodeficiency virus-infected infant macaques

21 January 2018

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Update on mucosal HIV vaccine vectors

21 January 2018

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Randomised, double-blind, safety and efficacy of a killed oral vaccine for enterotoxigenic E. Coli diarrhoea of travellers to Guatemala and Mexico.

21 January 2018

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Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road

21 January 2018

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21 January 2018

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BCG: the challenge continues

21 January 2018

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The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children

21 January 2018

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Disseminated bacille Calmette-Guérin disease in HIV-infected South African infants

21 January 2018

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Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization.

21 January 2018

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Evaluation of the safety and immunogenicity of a candidate tuberculosis vaccine, MVA85A, delivered by aerosol to the lungs of macaques

21 January 2018

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Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis

21 January 2018

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A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity

21 January 2018

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The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults

21 January 2018

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Mucosal delivery of antigen-coated nanoparticles to lungs confers protective immunity against tuberculosis infection in mice

21 January 2018

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Mucosal vaccination against tuberculosis using inert bioparticles

21 January 2018

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Plant-derived recombinant immune complexes as self-adjuvanting TB immunogens for mucosal boosting of BCG.

21 January 2018

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Oral vaccination with subunit vaccines protects animals against aerosol infection with Mycobacterium tuberculosis

21 January 2018

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Immunization with heat-killed Mycobacterium bovis bacille Calmette-Guerin (BCG) in Eurocine L3 adjuvant protects against tuberculosis

21 January 2018

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Mechanisms of mucosal and parenteral tuberculosis vaccinations: adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen

21 January 2018

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Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization

21 January 2018

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Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guérin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara

21 January 2018

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Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

21 January 2018

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Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

21 January 2018

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Immunology of tuberculosis

21 January 2018

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Characterization of the transcriptional initiation regions of genes for the major secreted protein antigens 85C and MPB51 of Mycobacterium bovis BCG.

21 January 2018

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Reversion of the attenuated and temperature-sensitive phenotypes of the Sabin type 3 strain of poliovirus in vaccinees

21 January 2018

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Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice

21 January 2018

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Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and esat-6.

21 January 2018

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Vaccines against mucosal infections

21 January 2018

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Phase I clinical trial in healthy adults of a nasal vaccine candidate containing recombinant hepatitis B surface and core antigens.

21 January 2018

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Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection

21 January 2018

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Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration

21 January 2018

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Mucosal delivery of microparticle encapsulated ESAT-6 induces robust cell-mediated responses in the lung milieu.

21 January 2018

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New adjuvants for human vaccines

21 January 2018

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Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04) compared to aluminium salt only

21 January 2018

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Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanoparticle vaccine delivery

21 January 2018

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Modulation of immune responses induced by DNA vaccine expressing glycoprotein B of Pseudorabies Virus via coadministration of IFN-gamma-associated cytokines.

21 January 2018

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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

21 January 2018

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Nasal boost with adjuvanted heat-killed BCG or arabinomannan–protein conjugate improves primary BCG-induced protection in C57BL/6 mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/IMT.14.62

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1 September 2017

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