(Q38265968)

1 September 2017

1 reference

title

Regulatory T cells in systemic lupus erythematosus. (English)

1 reference

systemic lupus erythematosus

1 September 2017

1 reference

Kim Ohl

1

1 reference

PubMed ID

25378177

1 September 2017

Klaus Tenbrock

series ordinal

2

1 reference

PubMed ID

25378177

1 September 2017

language of work or name

English

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publication date

15 December 2014

1 reference

European Journal of Immunology

1 September 2017

1 reference

1 September 2017

45

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1 September 2017

2

1 reference

1 September 2017

344-355

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Systemic lupus erythematosus.

1 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Pathogenetic aspects of systemic lupus erythematosus with an emphasis on regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

T cells as therapeutic targets in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Regulatory T cells in autoimmmunity*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Foxp3+ follicular regulatory T cells control the germinal center response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Epigenetic mechanisms of regulation of Foxp3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Epigenetic control of the foxp3 locus in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Phenotypical and functional specialization of FOXP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Control of tissue-localized immune responses by human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Natural versus adaptive regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Murine models of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Mouse models of systemic lupus erythematosus reveal a complex pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Cutting edge: Regulatory T cells directly suppress B cells in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Regulatory T cells in patients with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Reduced CD4+,CD25- T cell sensitivity to the suppressive function of CD4+,CD25high,CD127 -/low regulatory T cells in patients with active systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Balance between regulatory T and Th17 cells in systemic lupus erythematosus: the old and the new.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Phenotypic and functional analysis of CD4+ CD25- Foxp3+ T cells in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Are CD4+CD25-Foxp3+ cells in untreated new-onset lupus patients regulatory T cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Identity of mysterious CD4+CD25-Foxp3+ cells in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Increased CD45RA+ FoxP3(low) regulatory T cells with impaired suppressive function in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Phenotypic and functional properties of Helios+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-17-producing human peripheral regulatory T cells retain suppressive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Follicular helper CD4 T cells (TFH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

The role of somatic mutation in the pathogenic anti-DNA response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Imbalance of different types of CD4(+) forkhead box protein 3 (FoxP3)(+) T cells in patients with new-onset systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-6: regulator of Treg/Th17 balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Interferon-α suppresses cAMP to disarm human regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Stat3 phosphorylation mediates resistance of primary human T cells to regulatory T cell suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Regulatory T-cell-associated cytokines in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Activated CD4+CD25+ T cells selectively kill B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

T cells out of control--impaired immune regulation in the inflamed joint

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Function of CD4+,CD25+ Treg cells in MRL/lpr mice is compromised by intrinsic defects in antigen-presenting cells and effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Clinical significance of increased CD4+CD25-Foxp3+ T cells in patients with new-onset systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

The quantitative analysis of peripheral blood FOXP3-expressing T cells in systemic lupus erythematosus and rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Disturbed Th1, Th2, Th17 and T(reg) balance in patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Elimination of CD4(+)CD25(+) T cell accelerates the development of glomerulonephritis during the preactive phase in autoimmune-prone female NZB x NZW F mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201344280

7 January 2021

Identifiers

DOI

10.1002/EJI.201344280

1 reference

1 September 2017

1 reference

PubMed ID

25378177