(Q38268786)
Statements
1 reference
Narcotic analgestics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques (English)
Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques (English)
Tony L. Yaksh
32
39
Anatomical specificity as the critical determinant of the interrelationship between raphe lesions and morphine analgesia (English)
Adler
1975
44
692
Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor (English)
Akil
1972
33
579
Inhibition of behavioral and EEG activation induced by morphine acting on lower brainstem structures (English)
Albus
1972
12
53
Interaction between morphine and morphine antagonists after systemic and intraventricular application (English)
Albus
1970
67
373
The effect of DOPA on the spinal cord (English)
Andén
1966
67
398
Reciprocal effects on α- and γ-motoneurones of drugs influencing monoaminergic and cholinergic transmission (English)
Ardvisson
1966
124
53
Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla (English)
Atweh
1977
25
183
Effect of 6-hydroxydopamine on morphine analgesia (English)
Ayhan
1972
3
43
Reversal of morphine and stimulus-produced analgesia by subtotal spinal cord lesions (English)
Basbaum
1977
114
328
Inhibition of primate spinothalamic tract neurons by stimulation in the region of the nucleus raphe magnus (English)
Beall
1976
260
625
Analgesia induced in vivo by central administration of enkephalin in rat (English)
Belluzzi
1976
87
96
Regional distribution of tyrosine hydroxylase, norepinephrine and dopamine within the amygdaloid complex of the rat (English)
Ben-Ari
1975
122
523
Iontophoretic application of opiates to the locus coeruleus (English)
Bird
1977
31
111
Effect of 6-hydroxydopamine, 5,6-dihydroxy-tryptamine and raphe lesions on the antinociceptive actions of morphine in rats (English)
Blasig
1973
103
527
A caution to brain scientists: unsuspected hemorrhagic vascular damage resulting from mere electrode implantation (English)
Boast
1976
85
205
Differential projections of the nucleus raphe dorsalis and nucleus raphe centralis as revealed by autoradiography (English)
Bobillier
1975
31
288
A bulbar relay to the centre median (English)
Bowsher
1968
73
167
Actions and interactions of narcotic agonists and antagonists on brain stem neurones (English)
Bramwell
1974
261
425
Effects of microiontophoretically applied methionine-enkephalin on single neurones in rat brainstem (English)
Bradley
1976
0 references
117
193
The distribution within the brain of ferritin injected into cerebrospinal fluid compartments (English)
Brightman
1966
219
103
Effects of descending impulses on transmission through the spinocervical tract (English)
Brown
1971
261
423
Evidence for analgesic activity of enkephalin in the mouse (English)
Büscher
1976
212
211
Dose-dependent behavioral and analgesic effects produced by microinjection of morphine sulfate (MS) into the anterior thalamic nuclei (English)
Buxbaum
1970
52
1207
Effects of morphine and naloxone on dorsal horn neurones in the cat (English)
Calvillo
1974
2
15
Responses of bulboreticular units to somatic stimuli eliciting escape behavior in the cat (English)
Casey
1971
2
29
Escape elicited by bulboreticular stimulation in the cat (English)
Casey
1971
18
1473
Opiate receptor affinities and behavioral effects of enkephalin: structure-activity relationship of ten synthetic peptide analogues (English)
Chang
1976
139
259
An experimental silver study of the ascending projections of the central gray substance and adjacent tegmentum in the rat with observation in the cat (English)
1970
33
293
Spinal neurons specifically excited by noxious or thermal stimuli: marginal zones of the dorsal horn (English)
Christensen
1970
6
349
Inhibition of evoked potentials by caudate stimulation of its antagonism by centrally acting drugs (English)
Collins
1967
0 references
181
852
Effects of intraventricular and intrahypothalamic injection of noradrenaline and 5-HT on body temperature in unconscious rabbits (English)
Cooper
1965
4
23
Analgesia and hyperreactivity following morphine microinjection into mouse brain (English)
Criswell
1976
2
1054
Substance P: a naturally occurring transmitter in human spinal cord (English)
Cuello
1976
262
603
Effects of enkephalin and morphine on Renshaw cells in feline spinal cord (English)
Davies
1976
49
373
Evoking conditioned fear by electrical stimulation of subcortical structures in the monkey brain (English)
Delgado
1956
151
175
The tract of Lissauer in relation to sensory transmission in the dorsal horn of the spinal cord in the macaque monkey (English)
Denny-Brown
1973
58
383
Analgesia produced by morphine when acting from the liquor space (English)
1976
4
99
Periaqueductal gray lesions reduce morphine analgesia in the rat (English)
Dostrovsky
1977
246
222
Morphine blockade of amino acid putative transmitters on cat spinal cord sensory interneurones (English)
Dostrovsky
1973
26
551
Effects of spinal cord lesions on cutaneously elicited reflexes in the decerebrate cat. Tonic bulbospinal and spinobulbar inhibitory systems (English)
Dougherty
1970
264
456
Morphine, enkephalin and the substantia gelatinosa (English)
Duggan
1976
31
69
Pyramidal tract effects on interneurons in the cat lumbar dorsal horn (English)
Fetz
1968
120
49
Somatosensory properties of spinoreticular neurons in the cat (English)
Fields
1977
47
118
Some properties of spinal neurons projecting to the medial brain-stem reticular formation (English)
Fields
1975
68
334
Titration of aversive threshold in cats: escape and avoidance components (English)
Fields
1969
21
23
Enkephalin pentapeptides: a review of current evidence for a physiological role in vertebrate neurotransmission (English)
Frederickson
1977
194
440
Enkephalin induced depression of single neurons in brain areas with opiate receptors — antagonism by naloxone (English)
Frederickson
1976
14
259
The influence of raphe lesions on the effect of morphine on nociception and cortical ACH output (English)
Garau
1975
32
359
Decreased antinociceptive activity of morphine in rats pretreated intraventricularly with 5,6-dihydroxytryptamine, a long-lasting selective depletor of brain serotonin (English)
Genovese
1973
261
426
Effects of methionine-enkephalin and leucine-enkephalin compared with those of morphine on brainstem neurones in cat (English)
Gent
1976
102
282
Descending inhibitory influences on spinal reflexes during natural sleep (English)
Gianuinto
1964
37
597
Evoked bulbar reticular unit activity following delta fibre stimulation of peripheral somatosensory nerve in the cat (English)
Goldman
1972
20
171
Central monoamines and antinociceptive drug action (English)
Gorlitz
1972
29
171
Depression by morphine of activity in the ventrolateral tract evoked from cutaneous A fibres (English)
Grossmann
1974
24
67
The dependence of the anti-nociceptive effect of morphine and other analgesic agents on spinal motor activity after central monoamine depletion (English)
Grossman
1973
54
207
Organization of sensory modality in the reticular formation of the rat (English)
Groves
1973
61
417
Suppression by LSD of the inhibitory stimulation on certain spinal cord interneurons in the cat (English)
Guilbaud
1973
17
295
Central influences on spinal afferent conduction (English)
Hagbarth
1954
19
841
Morphine: ability to block neuronal activity evoked by a nociceptive stimulus (English)
Haigler
1976
11
215
Modification of escape from noxious stimuli after bulbar reticular formation lesions (English)
Halpern
1974
149
1
Cytoarchitectural subdivisions of the periaqueductal gray matter in the cat (English)
Hamilton
1970
152
45
Projections of the nuclei of the periaqueductal gray matter in the cat (English)
Hamilton
1973
139
105
Efferent connections of the periaqueductal gray matter in the cat (English)
Hamilton
1969
100
221
Analgetic effects of lanthanum: cross-tolerance with morphine (English)
Harris
1975
1
147
Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli (English)
Handwerker
1975
9
539
On the central sites for the antinociceptive action of morphine and fentanyl (English)
Herz
1970
64
64
Development of tolerance to the antinociceptive effect of morphine after intraventricular injection (English)
Herz
1973
9
284
Inhibitory and excitatory factors influencing the receptive fields of lamina 5 spinal cord cells (English)
Hillman
1969
190
889
Substance P: localization in the central nervous system and in some primary sensory neurons (English)
Hökfelt
1975
16
1823
Comparison of in vivo and in vitro parameters of opiate receptor binding in naive and tolerant/dependent rodents (English)
Höllt
1975
100
258
577
Identification of two related pentapeptides from the brain with potent opiate, agonist activity (English)
Hughes
1975
106
33
210
Long inhibitory and excitory pathways converging onto cat reticular and Deiters' neurons and their relevance to reticulofugal axons (English)
1970
107
21
413
Effects of fentanyl upon the spinal interneurons activated by Aδ afferent fibers of the cutaneous nerve of the cat (English)
Iwata
1971
109
192
261
Morphine-induced rotation in naive, nonlesioned rats (English)
Jacquet
1976
110
182
490
Morphine action at central nervous system sites in rat: analgesia or hyperalgesia depending on site and dose (English)
Jacquet
1973
111
185
1055
Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat (English)
Jacquet
1974
112
103
501
The periaqueductal gray: site of morphine analgesia and tolerance as shown by 2-way cross-tolerance between systemic and intracerebral injections (English)
Jacquet
1976
114
24
473
The effect of morphine on the activity evoked in the ventrolateral tract axons of the cat spinal cord (English)
Jurna
1976
115
12
983
Inhibition by morphine of repetitive activation of cat spinal motoneurones (English)
Jurna
1973
116
28
155
Excitatory connection from lateral hypothalamic selfstimulation sites to escape sites in medullary reticular formation (English)
Keene
1970
117
100
511
The course of ascending fibres in the spinal cord of the cat essential to the recognition of painful stimuli (English)
Kennard
1954
118
1
325
Neuroanatomical substrates of nociception in the spinal cord (English)
Kerr
1975
119
139
307
Functional variation in dermatomes in the macaque monkey following dorsal root lesions (English)
Kirk
1970
120
108
363
The projection of the A8, A9 and A10 dopaminergic cell bodies: evidence for a nigral-hypothalamic-median eminence dopaminergic pathway (English)
Kiser
1976
121
41
39
Lamina specific suppression of dorsal horn unit activity by morphine sulfate (English)
Kitahata
1974
122
12
400
A method for the combined staining of cells and fibers in the nervous system (English)
Klüver
1953
124
65
397
The effects of substance P and other peptides on spinal neurons of the frog (English)
Konishi
1974
126
47
457
Actions of morphine on the segmental reflex of the decerebrate-spinal cat (English)
Krivoy
1973
127
245
447
Regional distribution of opiate receptor binding in monkey and human brain (English)
Kuhar
1973
129
24
317
Effects of morphine and methotrimeprazine (levomepromazine) on the caudate-induced inhibition of the thalamic somatosensory evoked potentials (English)
Kuromi
1973
130
13
801
Structure-activity correlations of morphine-like analgetics based on efficiencies following intravenous and intraventricular application (English)
Kutter
1970
131
1
9
Retrograde axonal transport of horseradish peroxidase from spinal cord to brainstem cell groups in the cat (English)
Kuypers
1975
132
112
407
Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section (English)
LaMotte
1976
133
115
518
Differential effects of morphine on responses of dorsal horn lamina V type cells elicited by A and C fibre stimulation in the spinal cat (English)
LeBars
1976
134
113
293
Effects of morphine upon the lamina V type cells activities in the dorsal horn of the decerebrate cat (English)
LeBars
1976
135
98
261
Depressive effects of morphine upon lamina V cells activities in the dorsal horn of the spinal cat (English)
LeBars
1975
136
42
264
Medial bulboreticular response to peripherally applied noxious stimuli (English)
Le Blanc
1974
137
124
283
Evaluation of the periaqueductal central gray (PAG) as a morphine specific locus of action and examination of morphine-induced and stimulation-produced analgesia at coincident PAG loci (English)
Lewis
1977
139
50
441
Analgesia from electrical stimulation of the periaqueductal gray matter in the cat: behavioral observations and inhibitory effects on spinal cord interneurons (English)
Liebeskind
1973
140
27
135
Somatosensory evoked responses in the mesencephalic central gray matter of the rat (English)
Liebeskind
1971
142
28
41
Psychological and physiological mechanisms of pain (English)
Liebeskind
1977
143
23
353
Mesencephalic central gray lesions and fear-motivated behavior in rats (English)
Liebman
1970
145
22
249
The distribution of morphine following intracerebral microinjection (English)
Lomax
1966
146
2
215
Morphine analgesia, two-way avoidance, and consummatory behavior following lesions in the midbrain raphe nuclei of the rat (English)
Lorens
1974
148
5
35
Acute tolerance to morphine following systemic and intracerebral injection in the rat (English)
Lotti
1966
151
19
463
Opioid antagonists (English)
Martin
1967
152
11
195
Pharmacological studies of spinal cord adrenergic and cholinergic mechanisms and their relation to physical dependence on morphine (English)
Martin
1967
154
68
73
Pain reduction by focal electrical stimulation of the brain: an anatomical and behavioral analysis (English)
Mayer
1974
155
2
379
Central nervous system mechanisms of analgesia (English)
Mayer
1976
156
97
151
Reduction of the response of cat spinothalamic neurons to graded mechanical stimuli by electrical stimulation of the lower brain stem (English)
McCreery
1975
157
16
198
The action of reserpine and α-methyl-m-tyrosine, on the analgesic effect of morphine in rats and mice (English)
Medakovic
1964
159
83
718
Ascending axon degeneration following contralateral cordotomy (English)
Mehler
1960
160
21
353
Effects of discrete brainstem lesions in cats on perception of noxious stimulation (English)
Melzack
1958
161
150
971
Pain mechanisms: a new theory (English)
Melzack
1965
165
7
743
Microinjection of 3H-acetylcholine, 14C-serotonin and 3H-norepinephrine into the hypothalamus of the rat: diffusion into tissue and ventricles (English)
Myers
1971
166
93
140
Two types of inhibitory effects upon brain stem reticular neurons by low frequency stimulation of raphe nucleus in the rat (English)
Nakamura
1975
167
30
14
Sensations evoked by stimulation in the midbrain of man (English)
Nashold
1969
168
81
319
Hippocampal projections and related neural pathways to the midbrain in the cat (English)
Nauta
1958
169
124
71
Sites and mode of termination of reticulospinal fibers in the cat. An experimental study with silver impregnation methods (English)
Nyberg-Hansen
1965
170
221
8
Effects of hypothalamic lesions on escape behavior produced by midbrain electric stimulation (English)
Olds
1971
172
20
32
Behavioral and electrophysiological evidence of pain inhibition from midbrain stimulation in the cat (English)
Oliveras
1974
173
120
221
Opiate antagonist, naloxone, strongly reduces analgesia induced by stimulation of a raphe nucleus (centralis inferior) (English)
Oliveras
1977
174
1
139
Analgesia induced by electrical stimulation of the inferior centralis nucleus of the raphe in the cat (English)
Oliveras
1975
177
16
1765
An endogenous morphine-like factor in mammalian brain (English)
Pasternak
1975
181
44
131
The cholinergic system and nociception in the primate: interactions with morphine (English)
Pert
1975
183
44
139
Asymmetrical cross-tolerance between morphine and scopolamine induced antinociception in the primate: differential sites of action (English)
Pert
1975
184
80
135
Sites of morphine induced analgesia in the primate brain: relation to pain pathways (English)
Pert
1974
185
3
133
Localization of the antinociceptive action of morphine in primate brain (English)
Pert
1975
188
16
1849
Autoradiographic localization of the opiate receptor in rat brain (English)
Pert
1975
189
194
330
D-Ala-enkephaline-amide: a potent, long-lasting synthetic pentapeptide analgesic (English)
Pert
1976
190
23
333
Patterns of projection and branching of reticulospinal neurons (English)
Peterson
1975
191
107
137
The efferent connection of the nucleus raphe dorsalis (English)
Pierce
1976
192
17
406
Diffusion of non-electrolytes in brain tissue (English)
Pollay
1970
193
50
447
Specific nociceptive fibers projecting from spinal cord neurons to the brain: a possible pathway for pain (English)
Pomeranz
1973
194
48
201
Spinal cord coding of graded non-noxious and noxious temperature increases (English)
Price
1975
196
99
189
Ascending catecholamine systems and morphine analgesia (English)
Price
1975
197
65
542
New long-latency bulbospinal evoked potential blocked by serotonin antagonists (English)
Proudfit
1974
198
98
612
Morphine analgesia: blockade by raphe magnus lesions (English)
Proudfit
1975
202
30
83
Behavioral and EEG asymmetry following unilateral lesions of the forebrain and midbrain in cats (English)
Reeves
1971
204
100
279
The cytoarchitectonic atlas of the spinal cord in the cat (English)
Rexed
1954
208
130
156
Attenuation of morphine analgesia in rats by intraamygdaloid injection of dopamine (English)
Rogers
1977
213
61
91
Hyperthermic effects of morphine: set point manipulation by a direct spinal action (English)
Rudy
1977
214
97
177
Antagonism between Lioresal and substance P in rat spinal cord (English)
Saito
1975
215
25
175
Effects of intraventricular injected 6-OH-dopamine or midbrain raphe lesion on morphine analgesia in rats (English)
Samanin
1972
216
10
339
Reduced effect of morphine in midbrain raphe lesioned rats (English)
Samanin
1970
217
14
60
Enhancement by morphine of the central descending inhibitory influence on spinal sensory transmission (English)
Satoh
1971
218
82
378
Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats (English)
Satoh
1974
219
12
271
Etude des systèmes de renforcement négatif et de renforcement positif au niveau de la substance grise centrale chez le rat (English)
Schmitt
1974
222
54
66
Descending influences of periaqueductal gray matter and somatosensory cerebral cortex on neurones in trigeminal brain stem nuclei (English)
Sessle
1975
223
11
303
Analgesia and hyperreactivity produced by intracranial microinjections of morphine into the periaqueductal gray matter of the rat (English)
Sharpe
1974
224
110
273
Morphine and pain: effects on aspartate, GABA and glutamate in four discrete areas of mouse brain (English)
Sherman
1976
225
52
519
Morphine analgesia and the bulbospinal noradrenergic system: increase in the concentration of normetanephrine in the spinal cord of the rat caused by analgesics (English)
Shiomi
1974
227
106
189
The regional distribution of a morphine-like factor enkephalin in monkey brain (English)
Simantov
1976
228
107
650
A morphine-like factor “enkephalin” in rat brain: subcellular localization (English)
Simantov
1976
231
21
111
Morphine and meperidine on bulbospinal inhibition of the monosynaptic reflex (English)
Sinclair
1973
233
8
608
Stimulation of periaqueductal gray and hypothalamus (English)
Skultety
1963
234
13
212
Pain reactions upon stimulation of the tectum mesencephali (English)
Spiegel
1954
235
133
165
Attentive, affective, and adaptive behavior in the cat (English)
Sprague
1961
236
52
535
The impulse-blocking concentrations of anesthetics, alcohols, anticonvulsants, barbiturates, and narcotics on phrenic and sciatic nerves (English)
Staiman
1974
237
33
247
Accurate and reliable intracerebral delivery of minute volumes of drug solutions (English)
Swanson
1972
238
122
219
Neuronal and synaptic arrangement in the substantia gelatinosa Rolandi (English)
Szentágothai
1964
239
87
1
Regional distribution of substance P in the spinal cord and nerve roots of the cat and the effect of dorsal root section (English)
Takahashi
1975
241
17
67
Effects of morphine, L-DOPA and tetrabenazine on the lamina V cells of spinal dorsal horn (English)
Takagi
1975
243
20
85
Studies on the quantitative antagonism of analgesics by naloxone and diprenorphine (English)
Takemori
1972
245
10
357
Local, segmental and supraspinal interaction with a dorsolateral spinal cutaneous afferent system (English)
Taub
1964
246
260
158
Bilateral electroencephalographic response and unilateral tolerance to unilateral morphine injections (English)
Teitelbaum
1976
247
12
278
Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor (English)
Tenen
1968
250
12
123
Autoradiographic studies concerning the supraspinal site of the antinociceptive action of morphine when inhibiting the hindleg flexor reflex in rabbits (English)
Teschemacher
1973
253
33
65
The effect of dopaminergic stimulation and blockade on the nociceptive and antinociceptive response of mice (English)
Tulunay
1975
254
35
285
The effect of biogenic amine modifiers on morphine analgesia and its antagonism by naloxone (English)
Tulunay
1976
255
1
Stereotaxic mapping of the monoamine pathways in the rat brain (English)
Ungerstedt
1971
258
21
845
On the role of a central adrenergic action (English)
Vedernikov
1969
259
19
264
Antagonism of morphine analgesia by reserpine and α-methyl tyrosine and the role played by catecholamines in morphine analgesic action (English)
Verri
1967
260
113
563
Regional concentrations of noradrenaline and dopamine in the rat brain (English)
Versteeg
1976
261
13
140
Pain reactivity of monkeys after lesions to the dorsal and lateral columns of the spinal cord (English)
Vierck
1971
262
12
111
Differentiation between spinal and supraspinal sites of action of morphine when inhibiting the hindleg flexor reflex in rabbits (English)
Vigouret
1973
263
236
484
The effect of lowering 5-hydroxytryptamine content of the rat spinal cord on analgesia produced by morphine (English)
Vogt
1974
264
32
803
Responses of dorsal horn cells of Macaca mulatta to cutaneous and sural nerve A and C fiber stimuli (English)
Wagman
1969
265
188
403
The laminar organization of dorsal horn and effects of descending impulses (English)
Wall
1967
269
21
383
The development of tolerance to and of physical dependence on morphine following intraventricular injection in the rat (English)
Watanabe
1971
270
24
294
Neglect after mesencephalic reticular formation lesions (English)
Watson
1974
273
247
398
Similarity of morphine abstinence signs to thermoregulatory behavior (English)
1974
274
128
1575
Fractional escape and avoidance on a titration schedule (English)
Weiss
1958
275
6
563
Characteristics of aversive thresholds measured by a titration schedule (English)
Weiss
1963
279
2
435
Sites and mechanisms of action of morphine and related drugs in the central nervous system (English)
Wikler
1950
280
37
358
Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb (English)
Willis
1973
281
174
91
Reticulospinal neurones (English)
Wolstencroft
1964
282
Inhibition by etorphine of the discharge of dorsal horn neurons: effects on the neuronal response to both high- and low-threshold sensory input in the decerebrate spinal cat (English)
Yaksh
1978
283
Opiate receptors for behavioral analgesia resemble those related to the depression of spinal nociceptive neurons (English)
Yaksh
1978
284
104
367
Antagonism by methysergide and cinanserin of the antinociceptive action of morphine administered into the periaqueductal gray (English)
Yaksh
1976
285
2
593
The direct and specific opiate like effects of met5-enkephalin and analogues on the spinal cord of the rat (English)
Yaksh
1977
286
42
275
Tolerance and withdrawal in rats receiving morphine in the spinal subarachnoid space (English)
Yaksh
1977
287
41
399
Incomplete blockade by raphe lesions of the antinociceptive actions of systemic morphine (English)
Yaksh
1976
289
46
83
A quantitative analysis of the interaction between morphine and naloxone in rhesus monkeys on the shock titration test (English)
Yaksh
1977
290
192
1357
Analgesia mediated by a direct spinal action of narcotics (English)
Yaksh
1976
291
17
1031
Chronic catheterization of the spinal subarachnoid space (English)
Yaksh
1976
294
114
83
Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effects within the periaqueductal gray (English)
Yaksh
1976
297
4
23
Concurrent mapping of brain sites for sensitivity to the direct application of morphine and focal electrical stimulation in the production of antinociception in the rat (English)
Yeung
1977
298
Effect on the nociceptive threshold and EEG activity of the rat of morphine injected into the medial thalamus and the periaqueductal gray (English)
Yeung
1978
299
115
111
The mechanisms of inhibition of neuronal activity by opiates in the spinal cord of the cat (English)
Zieglgänsberger
1976
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Identifiers
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