(Q38269145)

1 September 2017

1 reference

title

Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance (English)

1 reference

1 September 2017

main subject

Gram-negative bacteria

0 references

multiple drug resistance

1 reference

based on heuristic

inferred from title

antibiotic resistance

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Laura Piddock

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Grace E Richmond

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

1 January 2014

1 reference

1 September 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

published in

Future Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

1165-1177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions

9 June 2020

cites work

1 reference

Preventing drug access to targets: cell surface permeability barriers and active efflux in bacteria

21 January 2018

1 reference

Molecular cloning and characterization of acrA and acrE genes of Escherichia coli

21 January 2018

1 reference

Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli

21 January 2018

1 reference

AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants

21 January 2018

1 reference

Expression of acrB, acrF, acrD, marA, and soxS in Salmonella enterica serovar Typhimurium: role in multiple antibiotic resistance.

21 January 2018

1 reference

AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar typhimurium DT104.

21 January 2018

1 reference

Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin

21 January 2018

1 reference

Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa

21 January 2018

1 reference

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance

21 January 2018

1 reference

Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454

21 January 2018

1 reference

Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump

21 January 2018

1 reference

CmeABC functions as a multidrug efflux system in Campylobacter jejuni

21 January 2018

1 reference

The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system.

21 January 2018

1 reference

The Burkholderia pseudomallei BpeAB-OprB efflux pump: expression and impact on quorum sensing and virulence

21 January 2018

1 reference

The AcrAB-TolC efflux system of Salmonella enterica serovar Typhimurium plays a role in pathogenesis.

21 January 2018

1 reference

Multidrug-resistance efflux pumps - not just for resistance

21 January 2018

1 reference

A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection

21 January 2018

1 reference

Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm

21 January 2018

1 reference

Inactivation of efflux pumps abolishes bacterial biofilm formation

21 January 2018

1 reference

Multidrug efflux pumps and resistance: regulation and evolution

21 January 2018

1 reference

Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria

21 January 2018

1 reference

Structure of the AcrAB–TolC multidrug efflux pump

21 January 2018

1 reference

The importance of efflux pumps in bacterial antibiotic resistance

21 January 2018

1 reference

Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria

21 January 2018

1 reference

Inner membrane efflux components are responsible for beta-lactam specificity of multidrug efflux pumps in Pseudomonas aeruginosa

21 January 2018

1 reference

Efflux-mediated resistance to tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1.

21 January 2018

1 reference

The AcrAB-TolC pump is involved in macrolide resistance but not in telithromycin efflux in Enterobacter aerogenes and Escherichia coli

21 January 2018

1 reference

Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates

21 January 2018

1 reference

A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron

21 January 2018

1 reference

Bacterial multidrug transport through the lens of the major facilitator superfamily

21 January 2018

1 reference

CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii

21 January 2018

1 reference

Emr, an Escherichia coli locus for multidrug resistance

21 January 2018

1 reference

The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs.

21 January 2018

1 reference

Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes

21 January 2018

1 reference

KpnEF, a new member of the Klebsiella pneumoniae cell envelope stress response regulon, is an SMR-type efflux pump involved in broad-spectrum antimicrobial resistance

21 January 2018

1 reference

Role of AbeS, a novel efflux pump of the SMR family of transporters, in resistance to antimicrobial agents in Acinetobacter baumannii

21 January 2018

1 reference

An H(+)-coupled multidrug efflux pump, PmpM, a member of the MATE family of transporters, from Pseudomonas aeruginosa

21 January 2018

1 reference

Gene cloning and characterization of VcrM, a Na+-coupled multidrug efflux pump, from Vibrio cholerae non-O1.

21 January 2018

1 reference

Molecular cloning and characterization of the HmrM multidrug efflux pump from Haemophilus influenzae Rd.

21 January 2018

1 reference

Efflux-mediated antibiotic resistance in Acinetobacter spp.

21 January 2018

1 reference

Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital

21 January 2018

1 reference

Selection of topoisomerase mutations and overexpression of adeB mRNA transcripts during an outbreak of Acinetobacter baumannii

21 January 2018

1 reference

AdeABC-mediated efflux and tigecycline MICs for epidemic clones of Acinetobacter baumannii

21 January 2018

1 reference

Contribution of efflux pumps, porins, and β-lactamases to multidrug resistance in clinical isolates of Acinetobacter baumannii.

21 January 2018

1 reference

Whole-genome comparison of two Acinetobacter baumannii isolates from a single patient, where resistance developed during tigecycline therapy

21 January 2018

1 reference

A truncated AdeS kinase protein generated by ISAba1 insertion correlates with tigecycline resistance in Acinetobacter baumannii

21 January 2018

1 reference

Tigecycline Efflux as a Mechanism for Nonsusceptibility in Acinetobacter baumannii

21 January 2018

1 reference

Influence of transcriptional activator RamA on expression of multidrug efflux pump AcrAB and tigecycline susceptibility in Klebsiella pneumoniae

21 January 2018

1 reference

MarA-mediated overexpression of the AcrAB efflux pump results in decreased susceptibility to tigecycline in Escherichia coli

21 January 2018

1 reference

Emergence of AcrAB-mediated tigecycline resistance in a clinical isolate of Enterobacter cloacae during ciprofloxacin treatment

21 January 2018

1 reference

The BpeEF-OprC efflux pump is responsible for widespread trimethoprim resistance in clinical and environmental Burkholderia pseudomallei isolates

21 January 2018

1 reference

Mechanisms of antibiotic resistance in Burkholderia pseudomallei: implications for treatment of melioidosis

21 January 2018

1 reference

Evidence for an efflux pump mediating multiple antibiotic resistance in Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

X-ray structure of EmrE supports dual topology model

21 January 2018

1 reference

Clinical strains of Pseudomonas aeruginosa overproducing MexAB-OprM and MexXY efflux pumps simultaneously

21 January 2018

1 reference

Two efflux systems expressed simultaneously in multidrug-resistant Pseudomonas aeruginosa

21 January 2018

1 reference

Interaction of CmeABC and CmeDEF in conferring antimicrobial resistance and maintaining cell viability in Campylobacter jejuni

21 January 2018

1 reference

Expression of the efflux pump genes cmeB, cmeF and the porin gene porA in multiple-antibiotic-resistant Campylobacter jejuni.

21 January 2018

1 reference

Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli

21 January 2018

1 reference

Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump

21 January 2018

1 reference

Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC

21 January 2018

1 reference

The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals

21 January 2018

1 reference

RamA, a member of the AraC/XylS family, influences both virulence and efflux in Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate

21 January 2018

1 reference

ramR mutations involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium

21 January 2018

1 reference

Regulation of RamA by RamR in Salmonella enterica serovar Typhimurium: isolation of a RamR superrepressor

21 January 2018

1 reference

RamA, which controls expression of the MDR efflux pump AcrAB-TolC, is regulated by the Lon protease

21 January 2018

1 reference

Proteolytic degradation of Escherichia coli transcription activators SoxS and MarA as the mechanism for reversing the induction of the superoxide (SoxRS) and multiple antibiotic resistance (Mar) regulons

21 January 2018

1 reference

Protein modulator of multidrug efflux gene expression in Pseudomonas aeruginosa

21 January 2018

1 reference

nalD encodes a second repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa

21 January 2018

1 reference

Regulation of multidrug efflux systems involved in multidrug and metal resistance of Salmonella enterica serovar Typhimurium

21 January 2018

1 reference

Effect of NlpE overproduction on multidrug resistance in Escherichia coli

21 January 2018

1 reference

Role of histone-like protein H-NS in multidrug resistance of Escherichia coli

21 January 2018

1 reference

AcrS/EnvR represses expression of the acrAB multidrug efflux genes in Escherichia coli

21 January 2018

1 reference

GolS controls the response to gold by the hierarchical induction of Salmonella-specific genes that include a CBA efflux-coding operon.

21 January 2018

1 reference

Functional characterization of the NfxB repressor of the mexCD-oprJ multidrug efflux operon of Pseudomonas aeruginosa

21 January 2018

1 reference

Histidine kinases and response regulator proteins in two-component signaling systems

21 January 2018

1 reference

Signal integration in bacterial two-component regulatory systems.

21 January 2018

1 reference

Direct interaction between sensor kinase proteins mediates acute and chronic disease phenotypes in a bacterial pathogen.

21 January 2018

1 reference

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

21 January 2018

1 reference

Two-component signal transduction

21 January 2018

1 reference

The baeSR two-component regulatory system activates transcription of the yegMNOB (mdtABCD) transporter gene cluster in Escherichia coli and increases its resistance to novobiocin and deoxycholate

21 January 2018

1 reference

EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli

21 January 2018

1 reference

Transcriptional regulation of drug efflux genes by EvgAS, a two-component system in Escherichia coli

21 January 2018

1 reference

SmeC, an outer membrane multidrug efflux protein of Stenotrophomonas maltophilia

21 January 2018

1 reference

Expression of the RND-type efflux pump AdeABC in Acinetobacter baumannii is regulated by the AdeRS two-component system

21 January 2018

1 reference

Transcription of emrKY is regulated by the EvgA-EvgS two-component system in Escherichia coli K-12.

21 January 2018

1 reference

Newly identified genes involved in the signal transduction of Escherichia coli K-12.

21 January 2018

1 reference

Contribution of mutation at amino acid 45 of AcrR to acrB expression and ciprofloxacin resistance in clinical and veterinary Escherichia coli isolates.

21 January 2018

1 reference

Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness

21 January 2018

1 reference

ramR mutations affecting fluoroquinolone susceptibility in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198.

21 January 2018

1 reference

Ciprofloxacin selects for multidrug resistance in Salmonella enterica serovar Typhimurium mediated by at least two different pathways

21 January 2018

1 reference

Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

Modulation of the mtrCDE-encoded efflux pump gene complex of Neisseria meningitidis due to a Correia element insertion sequence.

21 January 2018

1 reference

Enhanced expression of the multidrug efflux pumps AcrAB and AcrEF associated with insertion element transposition in Escherichia coli mutants Selected with a fluoroquinolone

21 January 2018

1 reference

Overexpression of the multidrug efflux operon acrEF by insertional activation with IS1 or IS10 elements in Salmonella enterica serovar typhimurium DT204 acrB mutants selected with fluoroquinolones

21 January 2018

1 reference

Antibiotic inducibility of the mexXY multidrug efflux operon of Pseudomonas aeruginosa: involvement of the MexZ anti-repressor ArmZ.

21 January 2018

1 reference

Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway

21 January 2018

1 reference

Indole induces the expression of multidrug exporter genes in Escherichia coli

21 January 2018

1 reference

Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses.

21 January 2018

1 reference

Regulation of the AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat

21 January 2018

1 reference

The crystal structure of multidrug-resistance regulator RamR with multiple drugs

21 January 2018

1 reference

Global challenge of multidrug-resistant Acinetobacter baumannii

21 January 2018

1 reference

Differential susceptibility to carbapenems due to the AdeABC efflux pump among nosocomial outbreak isolates of Acinetobacter baumannii in a Chinese hospital

21 January 2018

1 reference

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

21 January 2018

1 reference

Structure of the multidrug transporter EmrD from Escherichia coli

21 January 2018

1 reference

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

Structure of a cation-bound multidrug and toxic compound extrusion transporter

21 January 2018

1 reference

RND efflux pumps: structural information translated into function and inhibition mechanisms.

21 January 2018

1 reference

Structure and operation of bacterial tripartite pumps.

21 January 2018

1 reference

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

21 January 2018

1 reference

Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

21 January 2018

1 reference

Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations.

21 January 2018

1 reference

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

21 January 2018

1 reference

Inhibition of multidrug efflux as a strategy to prevent biofilm formation

21 January 2018

1 reference

Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa.

21 January 2018

1 reference

Mechanism of recognition of compounds of diverse structures by the multidrug efflux pump AcrB of Escherichia coli

21 January 2018

1 reference

Practical applications and feasibility of efflux pump inhibitors in the clinic--a vision for applied use.

21 January 2018

1 reference

Structural basis for the inhibition of bacterial multidrug exporters

21 January 2018

1 reference

Antibiotic inducibility of the MexXY multidrug efflux system of Pseudomonas aeruginosa: involvement of the antibiotic-inducible PA5471 gene product

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FMB.14.66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25405886%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference