(Q38271052)

1 September 2017

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title

GLUT2, glucose sensing and glucose homeostasis (English)

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1 September 2017

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Bernard Thorens

1

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1 September 2017

25 November 2014

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1 September 2017

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1 September 2017

58

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1 September 2017

2

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1 September 2017

221-232

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https://scigraph.springernature.com/pub.10.1007/s00125-014-3451-1

1 September 2017

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cites work

Food reward in the absence of taste receptor signaling

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12 December 2020

Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem

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12 December 2020

Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia

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12 December 2020

ChREBP rather than USF2 regulates glucose stimulation of endogenous L-pyruvate kinase expression in insulin-secreting cells

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12 December 2020

SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion

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12 December 2020

Intracerebroventricular administration of antisense oligodeoxynucleotide against GLUT2 glucose transporter mRNA reduces food intake, body weight change and glucoprivic feeding response in rats

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12 December 2020

Glucose-sensing neurons: are they physiologically relevant?

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12 December 2020

Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

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12 December 2020

Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain--an immunohistochemical study.

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12 December 2020

Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing

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12 December 2020

Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition

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12 December 2020

Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors

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12 December 2020

Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

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12 December 2020

Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations

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12 December 2020

Hindbrain neurons as an essential hub in the neuroanatomically distributed control of energy balance

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12 December 2020

N-Glycosylation modulates the membrane sub-domain distribution and activity of glucose transporter 2 in pancreatic beta cells.

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12 December 2020

Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels

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12 December 2020

Fanconi-Bickel syndrome and autosomal recessive proximal tubulopathy with hypercalciuria (ARPTH) are allelic variants caused by GLUT2 mutations.

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12 December 2020

Dissociation between sensing and metabolism of glucose in sugar sensing neurones.

1 reference

12 December 2020

Fanconi-Bickel syndrome--the original patient and his natural history, historical steps leading to the primary defect, and a review of the literature

1 reference

12 December 2020

Hypoglycemia-activated GLUT2 neurons of the nucleus tractus solitarius stimulate vagal activity and glucagon secretion.

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12 December 2020

The development and application of optogenetics

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12 December 2020

Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes

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12 December 2020

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

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12 December 2020

The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs.

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12 December 2020

Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig

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12 December 2020

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

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12 December 2020

Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease

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12 December 2020

Brain glucose sensing, counterregulation, and energy homeostasis

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12 December 2020

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes

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12 December 2020

A glucose sensor hiding in a family of transporters

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12 December 2020

Liver hyperplasia and paradoxical regulation of glycogen metabolism and glucose-sensitive gene expression in GLUT2-null hepatocytes. Further evidence for the existence of a membrane-based glucose release pathway.

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12 December 2020

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver

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12 December 2020

Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion

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12 December 2020

The fanconi syndrome associated with hepatic glycogenosis and abnormal metabolism of galactose

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12 December 2020

Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum

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12 December 2020

The SLC2 (GLUT) family of membrane transporters

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12 December 2020

Evolutionary structural and functional conservation of an ortholog of the GLUT2 glucose transporter gene (SLC2A2) in zebrafish

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12 December 2020

GLUT2 is a high affinity glucosamine transporter

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12 December 2020

Glucose transporters in the 21st Century

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12 December 2020

Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons

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12 December 2020

Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion

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12 December 2020

Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes

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12 December 2020

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport

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12 December 2020

Reduced beta-cell glucose transporter in new onset diabetic BB rats

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12 December 2020

Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

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12 December 2020

Chronic aminoaciduria (amino acid diabetes or nephrotic-glucosuric dwarfism) in glycogen storage and cystine disease

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12 December 2020

A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity

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12 December 2020

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice

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12 December 2020

Hepatic glucose sensing is required to preserve β cell glucose competence

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12 December 2020

Specific inhibition of GLUT2 in arcuate nucleus by antisense oligonucleotides suppresses nervous control of insulin secretion.

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12 December 2020

Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats

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12 December 2020

Fanconi-Bickel syndrome

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12 December 2020

Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study

1 reference

12 December 2020

Metabolism-independent sugar sensing in central orexin neurons.

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12 December 2020

Glucose has to be phosphorylated to activate glycogen synthase, but not to inactivate glycogen phosphorylase in hepatocytes

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12 December 2020

Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein

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12 December 2020

Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway

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12 December 2020

Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes

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12 December 2020

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence

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12 December 2020

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization

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12 December 2020

GLUT2 in pancreatic and extra-pancreatic gluco-detection (review).

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12 December 2020

Loss of glucose-induced insulin secretion and GLUT2 expression in transplanted -cells

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12 December 2020

Loss of sugar detection by GLUT2 affects glucose homeostasis in mice

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12 December 2020

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment

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12 December 2020

Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

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12 December 2020

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

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12 December 2020

Sensing of glucose in the brain

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12 December 2020

Differential organization of excitatory and inhibitory synapses within the rat dorsal vagal complex

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12 December 2020

Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels

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12 December 2020

Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia

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12 December 2020

Abnormalities of carbohydrate metabolism in idiopathic Fanconi syndrome

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12 December 2020

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

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12 December 2020

Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes

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12 December 2020

Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing

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12 December 2020

The effect of D-glucose on the firing rate of glucose-sensitive vagal afferents in the liver in comparison with the effect of 2-deoxy-D-glucose

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12 December 2020

Participation of Hepatic Glucoreceptors in the Control of Intake of Food

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12 December 2020

ChREBP mediates glucose-stimulated pancreatic β-cell proliferation

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12 December 2020

Metabolic signaling in fuel-induced insulin secretion

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12 December 2020

Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants

1 reference

12 December 2020

An anterograde tracing study of the vagal innervation of rat liver, portal vein and biliary system

1 reference

12 December 2020

Adaptations of glucose and fatty acid metabolism during perinatal period and suckling-weaning transition

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12 December 2020

Hepatic gene regulation by glucose and polyunsaturated fatty acids: a role for ChREBP.

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12 December 2020

The receptors and cells for mammalian taste

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12 December 2020

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

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12 December 2020

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells

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12 December 2020

Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch

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12 December 2020

Solitary tract nucleus sensitivity to moderate changes in glucose level

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12 December 2020

The large intracytoplasmic loop of the glucose transporter GLUT2 is involved in glucose signaling in hepatic cells

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12 December 2020

Hypoglycemia in diabetes.

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12 December 2020

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

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12 December 2020

Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding.

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12 December 2020

Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis

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12 December 2020

Detection of extracellular glucose by GLUT2 contributes to hypothalamic control of food intake

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12 December 2020

Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study

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12 December 2020

Functional and chemical anatomy of the afferent vagal system

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12 December 2020

Expression of glucose transporter isoform GLUT-2 and glucokinase genes in human brain.

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12 December 2020

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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12 December 2020

10.1007/S00125-014-3451-1

Identifiers

DOI

1 reference

PubMed ID

25421524

Dimensions Publication ID

1 September 2017

0 references

1 reference

PubMed ID

25421524