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TMEM16 proteins: unknown structure and confusing functions.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
review article
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Europe PubMed Central
title
TMEM16 proteins: unknown structure and confusing functions
(English)
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stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
main subject
protein structure
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author
Alessandra Picollo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
author name string
Mattia Malvezzi
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2
1 reference
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Europe PubMed Central
PMC publication ID
4277903
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
Alessio Accardi
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3
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stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
language of work or name
English
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publication date
17 October 2014
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Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
published in
Journal of Molecular Biology
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stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
volume
427
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
page(s)
94-105
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Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
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The Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis
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TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing
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TMEM16A alternative splicing coordination in breast cancer.
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Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC)
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TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation
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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction
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Anoctamin 6 is an essential component of the outwardly rectifying chloride channel
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Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome
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6 September 2017
Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
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6 September 2017
Calcium-dependent phospholipid scrambling by TMEM16F
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6 September 2017
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A
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6 September 2017
TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels
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6 September 2017
TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells
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TMEM16B induces chloride currents activated by calcium in mammalian cells
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Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
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TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
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6 September 2017
TMEM16A confers receptor-activated calcium-dependent chloride conductance
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6 September 2017
Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level
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6 September 2017
A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors
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6 September 2017
A complex peptide-sorting signal, but no mRNA signal, is required for the Sec-independent transport of Ist2 from the yeast ER to the plasma membrane
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Scott syndrome, a bleeding disorder caused by defective scrambling of membrane phospholipids
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6 September 2017
NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate
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6 September 2017
Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives
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6 September 2017
Inhibition of Ca(2+)-activated Cl(-) channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma
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6 September 2017
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.
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6 September 2017
TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation
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14 September 2017
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A.
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14 September 2017
Membrane phosphatidylserine regulates surface charge and protein localization
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14 September 2017
Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents
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27 September 2017
Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity.
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23 June 2018
The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration
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23 June 2018
The voltage dependence of the TMEM16B/anoctamin2 calcium-activated chloride channel is modified by mutations in the first putative intracellular loop.
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23 June 2018
Permeant anions control gating of calcium-dependent chloride channels.
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23 June 2018
Dynamics of calcium regulation of chloride currents in Xenopus oocytes.
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23 June 2018
Voltage-activated and calcium-activated currents studied in solitary rod inner segments from the salamander retina.
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23 June 2018
Membrane asymmetry and blood coagulation
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PubMed Central
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23 June 2018
Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
31 August 2018
Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
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31 August 2018
TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
31 August 2018
TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channel
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
31 August 2018
Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
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31 August 2018
Explaining calcium-dependent gating of anoctamin-1 chloride channels requires a revised topology
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
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31 August 2018
Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
31 August 2018
Store-mediated calcium entry in the regulation of phosphatidylserine exposure in blood cells from Scott patients.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
31 August 2018
CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4277903
retrieved
3 December 2018
Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25451786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A calcium-dependent transient outward current in Xenopus laevis oocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25451786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JMB.2014.09.028
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
PMC publication ID
4277903
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
PubMed publication ID
25451786
1 reference
stated in
Europe PubMed Central
PMC publication ID
4277903
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25451786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 February 2020
ResearchGate publication ID
267760763
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