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English
TCR signal quantity and quality in CD4(+) T cell differentiation.
scientific article published on 22 October 2014
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
TCR signal quantity and quality in CD4+ T cell differentiation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
main subject
cell differentiation
1 reference
based on heuristic
inferred from title
author
Marc K. Jenkins
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
author name string
Noah J Tubo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
publication date
22 October 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
published in
Trends in Immunology
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stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
volume
35
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
issue
12
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
page(s)
591-596
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
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TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation
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T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex
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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.
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6 September 2017
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells
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Follicular helper CD4 T cells (TFH)
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6 September 2017
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.
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One naive T cell, multiple fates in CD8+ T cell differentiation.
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6 September 2017
Fast on-rates allow short dwell time ligands to activate T cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Differentiation of effector CD4 T cell populations (*)
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
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PubMed Central
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6 September 2017
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire
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6 September 2017
The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
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Cytokine-secreting follicular T cells shape the antibody repertoire
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
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PubMed Central
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6 September 2017
IL-17 and Th17 Cells
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PubMed Central
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6 September 2017
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice
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6 September 2017
Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance
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6 September 2017
Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection
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PubMed Central
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6 September 2017
Evolutionarily conserved amino acids that control TCR-MHC interaction
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
How TCRs bind MHCs, peptides, and coreceptors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Positive and negative selection of T cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
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6 September 2017
Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model
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PubMed Central
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6 September 2017
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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6 September 2017
T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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14 September 2017
The regulation of immunity to Leishmania major
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
retrieved
14 September 2017
Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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23 June 2018
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
retrieved
23 June 2018
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
retrieved
23 June 2018
Complete but curtailed T-cell response to very low-affinity antigen
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
retrieved
23 June 2018
Fine tuning of TCR signaling by CD5.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
retrieved
23 June 2018
A kinetic basis for T cell receptor repertoire selection during an immune response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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23 June 2018
IL-4 directs the development of Th2-like helper effectors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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23 June 2018
Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major.
1 reference
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PubMed Central
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23 June 2018
Sustained interactions between T cell receptors and antigens promote the differentiation of CD4⁺ memory T cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
Heterogeneous differentiation patterns of individual CD8+ T cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
Disparate individual fates compose robust CD8+ T cell immunity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
Treg cells meet their limit
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PubMed Central
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31 August 2018
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.
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31 August 2018
Different T cell receptor signals determine CD8+ memory versus effector development
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406772
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31 August 2018
Ligand recognition by alpha beta T cell receptors
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PubMed Central
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31 August 2018
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25457838
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.IT.2014.09.008
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
PMC publication ID
4406772
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
PubMed publication ID
25457838
1 reference
stated in
Europe PubMed Central
PMC publication ID
4406772
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25457838%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 February 2020
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