(Q38287809)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author

Christopher D. Kontos

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Xi-Lin Niu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Kevin G Peters

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

24 June 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

31768-31773

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development.

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Angiopoietin-1 protects the adult vasculature against plasma leakage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Vascular-specific growth factors and blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Identifying substrates for endothelium-specific Tie-2 receptor tyrosine kinase from phage-displayed peptide libraries for high throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Ligand-independent activation of fibroblast growth factor receptor-2 by carboxyl terminal alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

The transforming potential of the c-erbB-2 protein is regulated by its autophosphorylation at the carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Identification of a putative Syp substrate, the PDGF beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Allelic and locus heterogeneity in inherited venous malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203995200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203995200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082108%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference