(Q38290539)

1 September 2017

1 reference

title

The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis (English)

1 reference

1 September 2017

0 references

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

James D Williamson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Laura R Sadofsky

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

16 December 2014

1 reference

Experimental Lung Research

1 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

57-73

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis

11 June 2020

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Effect of chelating agents and metal ions on the degradation of DNA by bleomycin

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Definition of the intermediates and mechanism of the anticancer drug bleomycin using nuclear resonance vibrational spectroscopy and related methods

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Direct hydrogen-atom abstraction by activated bleomycin: an experimental and computational study

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Bleomycin: new perspectives on the mechanism of action

21 January 2018

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Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety

21 January 2018

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Identification of a plasma membrane protein that specifically binds bleomycin

21 January 2018

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Internalisation of the bleomycin molecules responsible for bleomycin toxicity: a receptor-mediated endocytosis mechanism

21 January 2018

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The human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5

21 January 2018

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Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity

21 January 2018

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Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization

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Bleomycin-induced pneumonitis

21 January 2018

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A clinical review of bleomycin--a new antineoplastic agent

21 January 2018

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Ultrastructure of pulmonary bleomycin toxicity.

21 January 2018

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Fatal bleomycin pulmonary toxicity in the west of Scotland 1991-95: a review of patients with germ cell tumours

21 January 2018

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Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis

21 January 2018

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Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease

21 January 2018

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Role of E-selectin in bleomycin induced lung fibrosis in mice

21 January 2018

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Time course of bleomycin-induced lung fibrosis.

21 January 2018

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Static and dynamic mechanics of the murine lung after intratracheal bleomycin

21 January 2018

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Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation

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Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis.

21 January 2018

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Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells

21 January 2018

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Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent.

21 January 2018

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Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers

21 January 2018

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Losartan attenuates bleomycin induced lung fibrosis by increasing prostaglandin E2 synthesis

21 January 2018

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Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2.

21 January 2018

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Bleomycin-induced apoptosis of alveolar epithelial cells requires angiotensin synthesis de novo

21 January 2018

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TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells.

21 January 2018

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Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice

21 January 2018

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Intratracheal transplantation of alveolar type II cells reverses bleomycin-induced lung fibrosis

21 January 2018

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Animal models of acute lung injury

21 January 2018

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Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

21 January 2018

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Upregulation of Fas-signalling molecules in lung epithelial cells from patients with idiopathic pulmonary fibrosis

21 January 2018

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Angiotensin-TGF-beta 1 crosstalk in human idiopathic pulmonary fibrosis: autocrine mechanisms in myofibroblasts and macrophages.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Early response to bleomycin is characterized by different cytokine and cytokine receptor profiles in lungs.

21 January 2018

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WNT/β-catenin signaling induces IL-1β expression by alveolar epithelial cells in pulmonary fibrosis

21 January 2018

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Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

21 January 2018

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Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis.

21 January 2018

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Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Lung interleukin-4 gene expression in a murine model of bleomycin-induced pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanism

21 January 2018

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Alteration of proteoglycan synthesis in human lung fibroblasts induced by interleukin-1beta and tumor necrosis factor-alpha

21 January 2018

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Costimulation of fibroblast collagen and transforming growth factor beta1 gene expression by monocyte chemoattractant protein-1 via specific receptors

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2.

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.

21 January 2018

1 reference

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C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Early and late changes of MMP-2 and MMP-9 in bleomycin-induced pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Eosinophil chemotactic activity in bronchoalveolar lavage from idiopathic pulmonary fibrosis is dependent on cytokine priming of eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Comparison of cell profiles of bronchial and bronchoalveolar lavage fluids between normal subjects and patients with idiopathic pulmonary fibrosis.

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Prognostic role of eosinophils in pulmonary fibrosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Bronchoalveolar lavage fluid cell counts in cryptogenic fibrosing alveolitis and their relation to therapy

21 January 2018

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Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

CD8+ T lymphocytes in lung tissue from patients with idiopathic pulmonary fibrosis

21 January 2018

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Cell profiles of bronchoalveolar lavage fluid as prognosticators of idiopathic pulmonary fibrosis/usual interstitial pneumonia among Japanese Patients

21 January 2018

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Usual interstitial pneumonitis is a T-cell alveolitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Effect of lung T lymphocytes on fibroblasts in idiopathic pulmonary fibrosis and extrinsic allergic alveolitis

21 January 2018

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CD8+ T lymphocytes in bronchoalveolar lavage in idiopathic pulmonary fibrosis

21 January 2018

1 reference

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Immunohistological analysis of lung tissue from patients with cryptogenic fibrosing alveolitis suggesting local expression of immune hypersensitivity

21 January 2018

1 reference

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Plasma B lymphocyte stimulator and B cell differentiation in idiopathic pulmonary fibrosis patients

21 January 2018

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Localisation of a pulmonary autoantigen in cryptogenic fibrosing alveolitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Increased expression of activation markers and adhesion molecules on lung T-cells compared with blood in the normal rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

The mercurial nature of neutrophils: still an enigma in ARDS?

21 January 2018

1 reference

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Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation

21 January 2018

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https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation

21 January 2018

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In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-beta in the lung.

21 January 2018

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Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation

21 January 2018

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Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis

21 January 2018

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Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation

21 January 2018

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Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters

21 January 2018

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Therapeutic effect of a peptide inhibitor of TGF-β on pulmonary fibrosis

21 January 2018

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Role of the chemokine receptor CXCR2 in bleomycin-induced pulmonary inflammation and fibrosis

21 January 2018

1 reference

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Attenuation of bleomycin induced pulmonary fibrosis in mice using the heme oxygenase inhibitor Zn-deuteroporphyrin IX-2,4-bisethylene glycol.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36

21 January 2018

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Novel therapeutic approaches for pulmonary fibrosis

21 January 2018

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Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha.

21 January 2018

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Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis

21 January 2018

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Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis.

21 January 2018

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Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways.

21 January 2018

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Transforming growth factor-beta antagonizes alveolar type II cell proliferation induced by keratinocyte growth factor

21 January 2018

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Transforming growth factor-beta signal transduction in epithelial cells.

21 January 2018

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Regulation of PDGF and its receptors in fibrotic diseases

21 January 2018

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Gene expression of profibrotic mediators in bronchiolitis obliterans syndrome after lung transplantation

21 January 2018

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Platelet-derived growth factor in idiopathic pulmonary fibrosis

21 January 2018

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Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Endothelin in pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Endothelin-1 and endothelin-3 induce chemotaxis and replication of pulmonary artery fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Potential role of endothelin-1 in pulmonary fibrosis: from the bench to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Different expression of endothelin in the bronchoalveolar lavage in patients with pulmonary diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

BUILD-3: a randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

The myofibroblast in pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Molecular targets in pulmonary fibrosis: the myofibroblast in focus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Idiopathic pulmonary fibrosis: new insights in its pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Evolving concepts of apoptosis in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Bleomycin-induced interstitial pneumonia in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Genomic responses in mouse models poorly mimic human inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01902148.2014.979516

Determinants of bronchoalveolar lavage cellularity in idiopathic pulmonary fibrosis

21 January 2018

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/citations/10.1152/JAPPL.1991.71.5.1688

Identifiers

DOI

10.3109/01902148.2014.979516

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514507%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference