(Q38290716)

1 September 2017

title

ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair (English)

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1 September 2017

Jeremy M Stark

1

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1 September 2017

Peng Hu

2

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1 September 2017

Andrew J Pierce

3

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1 September 2017

Mary Ellen Moynahan

4

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1 September 2017

Nathan Ellis

5

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1 September 2017

Maria Jasin

6

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1 September 2017

language of work or name

English

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publication date

28 March 2002

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

277

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1 September 2017

issue

23

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1 September 2017

page(s)

20185-20194

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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 September 2017

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Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

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Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

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Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

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RecA protein promotes the regression of stalled replication forks in vitro

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Brca1 controls homology-directed DNA repair

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

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The essential functions of human Rad51 are independent of ATP hydrolysis

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Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

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Expression vector system based on the chicken beta-actin promoter directs efficient production of interleukin-5.

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Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

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Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

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Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations

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Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

21 January 2018

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Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

21 January 2018

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Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair

21 January 2018

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Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase.

21 January 2018

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XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

21 January 2018

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Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

21 January 2018

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Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

21 January 2018

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21 January 2018

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Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

21 January 2018

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Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

21 January 2018

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Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange

21 January 2018

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Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair

21 January 2018

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Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break

21 January 2018

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Aberrant double-strand break repair in rad51 mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

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RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112132200

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112132200

Binding of Rad51p to DNA. Interaction of Rad51p with single- and double-stranded DNA.

21 January 2018

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DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis: on the importance of not getting stuck

21 January 2018

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BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

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Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

21 January 2018

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Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

21 January 2018

1 reference

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Role of RAD51 in sister-chromatid exchanges in mammalian cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112132200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112132200

Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112132200

21 January 2018

Identifiers

DOI

10.1074/JBC.M112132200

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1 September 2017

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