(Q38292157)

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Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli.

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scholarly article

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7 December 2019

Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839759%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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phosphorylation

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1

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7 December 2019

author name string

Steven S Gross

2

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7 December 2019

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11 February 2002

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7 December 2019

Journal of Biological Chemistry

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7 December 2019

277

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7 December 2019

21

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7 December 2019

19087-19094

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7 December 2019

The nitric oxide synthase family of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Calmodulin is a subunit of nitric oxide synthase from macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

An autoinhibitory control element defines calcium-regulated isoforms of nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Removal of a putative inhibitory element reduces the calcium-dependent calmodulin activation of neuronal nitric-oxide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Estrogen induces the Akt-dependent activation of endothelial nitric-oxide synthase in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Characterization of rat neuronal nitric oxide synthase expressed in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Nitric oxide synthases: properties and catalytic mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Activation of myosin light chain kinase and nitric oxide synthase activities by engineered calmodulins with duplicated or exchanged EF hand pairs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

The C terminus of mouse macrophage inducible nitric-oxide synthase attenuates electron flow through the flavin domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

The C termini of constitutive nitric-oxide synthases control electron flow through the flavin and heme domains and affect modulation by calmodulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200258200

21 January 2018

Identifiers

10.1074/JBC.M200258200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839759%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11839759%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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