(Q38294671)

1 September 2017

title

Determination of active site residues in Escherichia coli endonuclease VIII. (English)

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1 September 2017

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Sarah Burgess

1

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1 September 2017

Pawel Jaruga

2

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1 September 2017

M L Dodson

3

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1 September 2017

Miral Dizdaroglu

4

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1 September 2017

R Stephen Lloyd

5

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1 September 2017

language of work or name

English

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publication date

15 November 2001

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

277

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1 September 2017

issue

4

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1 September 2017

page(s)

2938-2944

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Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage

1 September 2017

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Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization

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MutM, a protein that prevents G C→T A transversions, is formamidopyrimidine-DNA glycosylase

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Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals

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Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants

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Substrate specificity and excision kinetics of Escherichia coli endonuclease VIII (Nei) for modified bases in DNA damaged by free radicals

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Characterization of endonuclease III (nth) and endonuclease VIII (nei) mutants of Escherichia coli K-12.

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Recognition of formamidopyrimidine by Escherichia coli and mammalian thymine glycol glycosylases. Distinctive paired base effects and biological and mechanistic implications.

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Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue

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Role of the N-terminal proline residue in the catalytic activities of the Escherichia coli Fpg protein

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Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII

21 January 2018

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Characterization ofEscherichia coliEndonuclease VIII

21 January 2018

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NH2-terminal proline acts as a nucleophile in the glycosylase/AP-lyase reaction catalyzed by Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) protein

21 January 2018

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Involvement of phylogenetically conserved acidic amino acid residues in catalysis by an oxidative DNA damage enzyme formamidopyrimidine glycosylase

21 January 2018

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Mechanism of action of Escherichia coli endonuclease III

21 January 2018

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Kinetic isotope effect studies of the reaction catalyzed by uracil DNA glycosylase: evidence for an oxocarbenium ion-uracil anion intermediate

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21 January 2018

Identifiers

DOI

10.1074/JBC.M110499200

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1 September 2017

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