(Q38295615)

1 September 2017

title

Active site residues of human brain hexokinase as studied by site-specific mutagenesis (English)

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1 September 2017

Zeng C

1

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1 September 2017

Fromm HJ

series ordinal

2

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1 September 2017

language of work or name

English

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publication date

1 May 1995

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

270

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1 September 2017

issue

18

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1 September 2017

page(s)

10509-10513

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The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression.

1 September 2017

cites work

1 reference

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Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae.

21 January 2018

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Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous

21 January 2018

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Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase

21 January 2018

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Complete amino acid sequence of the type II isozyme of rat hexokinase, deduced from the cloned cDNA: comparison with a hexokinase from novikoff ascites tumor.

21 January 2018

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Complete amino acid sequence of the type III isozyme of rat hexokinase, deduced from the cloned cDNA.

21 January 2018

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Purification and properties of pig-heart hexokinase

21 January 2018

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Specificity for the glucose-6-P inhibition site of hexokinase.

21 January 2018

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Purification and properties of rat skeletal muscle hexokinase

21 January 2018

1 reference

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Inhibition of brain hexokinase by a multisubstrate analog results from binding to a discrete regulatory site.

21 January 2018

1 reference

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A refined model of the sugar binding site of yeast hexokinase B

21 January 2018

1 reference

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Structure of a complex between yeast hexokinase A and glucose. II. Detailed comparisons of conformation and active site configuration with the native hexokinase B monomer and dimer

21 January 2018

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Mammalian hexokinase 1: Evolutionary conservation and structure to function analysis

21 January 2018

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Effect of ligands on the reactivity of essential sulfhydryls in brain hexokinase. Possible interaction between substrate binding sites

21 January 2018

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Reaction of brain hexokinase with tetranitromethane: Oxidation of essential thiol groups

21 January 2018

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Inactivation of brain hexokinase by an adenosine 5'-triphosphate analog

21 January 2018

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Rat brain hexokinase: location of the substrate hexose binding site in a structural domain at the C-terminus of the enzyme.

21 January 2018

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Rat brain hexokinase: amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase.

21 January 2018

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Isolation and characterization of the discrete N- and C-terminal halves of rat brain hexokinase: retention of full catalytic activity in the isolated C-terminal half

21 January 2018

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A recombinant human ‘mini’-hexokinase is catalytically active and regulated by hexose 6-phosphates

21 January 2018

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An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins

21 January 2018

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Atomic structure of the actin:DNase I complex

21 January 2018

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21 January 2018

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Expression of human brain hexokinase in Escherichia coli: purification and characterization of the expressed enzyme

21 January 2018

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DNA sequencing with chain-terminating inhibitors

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Studies on the kinetics and mechanism of orthophosphate activation of bovine brain hexokinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.18.10509

Hexokinase of human erythrocytes. Purification, kinetic model and its application to the conditions in the cell.

21 January 2018

1 reference

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Mapping of glucose and glucose-6-phosphate binding sites on bovine brain hexokinase. A 1H- and 31P-NMR investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.18.10509

Kinetic evidence that the high-affinity glucose 6-phosphate site on hexokinase I Is the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.18.10509

21 January 2018

Identifiers

DOI

10.1074/JBC.270.18.10509

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1 September 2017

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