(Q38296034)

1 September 2017

title

Computational study on mechanism of G-quartet oligonucleotide T40214 selectively targeting Stat3. (English)

1 reference

1 September 2017

Qiqing Zhu

1

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1 September 2017

Naijie Jing

series ordinal

2

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1 September 2017

publication date

1 October 2007

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Journal of Computer - Aided Molecular Design

1 September 2017

published in

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1 September 2017

volume

21

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1 September 2017

issue

10-11

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1 September 2017

page(s)

641-648

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https://scigraph.springernature.com/pub.10.1007/s10822-007-9147-6

1 September 2017

exact match

0 references

cites work

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

21 January 2018

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Structure of the unphosphorylated STAT5a dimer

21 January 2018

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12 December 2020

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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Structure of an activated Dictyostelium STAT in its DNA-unbound form

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12 December 2020

The Protein Data Bank

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Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer

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Transcription factors as targets for cancer therapy

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

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Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells

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Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

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The role of STATs in transcriptional control and their impact on cellular function

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

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12 December 2020

G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis

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12 December 2020

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors.

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

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Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

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Stats: transcriptional control and biological impact

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The STATs of cancer--new molecular targets come of age

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Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides.

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Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug

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Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

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Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

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Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

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12 December 2020

10.1007/S10822-007-9147-6

Identifiers

DOI

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1 September 2017

DBLP publication ID

journals/jcamd/ZhuJ07

1 reference

DBLP Dataset 2021-01-02

release_yl6gtg3obbdtrhreqtoiyoumzi

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yl6gtg3obbdtrhreqtoiyoumzi

24 November 2022

mapped directly with Wikidata item

1 reference