(Q38296407)

1 September 2017

title

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols (English)

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1 September 2017

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3

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1 September 2017

Janowski BA

1

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1 September 2017

Shan B

series ordinal

2

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1 September 2017

language of work or name

English

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publication date

27 September 2001

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

276

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1 September 2017

issue

48

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1 September 2017

page(s)

45408-45416

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Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway

1 September 2017

cites work

1 reference

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SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

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Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

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Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

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Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol

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Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

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Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

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Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1.

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The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

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Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

21 January 2018

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Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts

21 January 2018

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21 January 2018

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21 January 2018

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Transport-Dependent Proteolysis of SREBP

21 January 2018

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Overexpression of membrane domain of SCAP prevents sterols from inhibiting SCAP.SREBP exit from endoplasmic reticulum

21 January 2018

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21 January 2018

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Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

21 January 2018

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Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

21 January 2018

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19 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0021-9258(19)84879-2

Identifiers

DOI

10.1074/JBC.M108348200

1 reference

1 September 2017

1 reference