(Q38298848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Carbohydrate residues downstream of the terminal Galalpha(1,3)Gal epitope modulate the specificity of xenoreactive antibodies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

main subject

Methyl alpha-galactoside

1 reference

alpha-D-galactosyl-(1->3)-D-galactose

ChEBI ID

55507

1 reference

alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-Glcp

ChEBI ID

53651

1 reference

1 reference

alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-Glc

ChEBI ID

28053

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Elizabeth Yuriev

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Paul A. Ramsland

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Pei-Xiang Xing

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Ian F C McKenzie

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Mauro S Sandrin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

1 reference

28 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

Immunology & Cell Biology

4 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

85

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

623-632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724458%20AND%20SRC:MED&resulttype=core&format=json

Characteristics of protein-carbohydrate interactions as a basis for developing novel carbohydrate-based antirejection therapies

4 January 2020

cites work

1 reference

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Gal alpha (1,3)Gal, the major xenoantigen(s) recognised in pigs by human natural antibodies

21 January 2018

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Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes

21 January 2018

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Alpha1,3-galactosyltransferase knockout pigs are available for xenotransplantation: are glycosyltransferases still relevant?

21 January 2018

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Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man.

21 January 2018

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Tumor-Associated Carbohydrate Antigens

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Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours

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Blood brothers: carbohydrates in xenotransplantation and cancer immunotherapy

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21 January 2018

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Oocyte Gal alpha 1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse.

21 January 2018

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21 January 2018

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alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies

21 January 2018

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Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations

21 January 2018

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Production of alpha 1,3-galactosyltransferase-deficient pigs

21 January 2018

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The molecular basis for galalpha(1,3)gal expression in animals with a deletion of the alpha1,3galactosyltransferase gene.

21 January 2018

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Chewing the fat on natural killer T cell development.

21 January 2018

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Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency

21 January 2018

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The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells

21 January 2018

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Lysosomal glycosphingolipid recognition by NKT cells

21 January 2018

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Fate of alphaGal +/+ pancreatic islet grafts after transplantation into alphaGal knockout mice

21 January 2018

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Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection

21 January 2018

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Cutting Edge: NK cells mediate IgG1-dependent hyperacute rejection of xenografts.

21 January 2018

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Anti-Gal antibodies in humans and 1, 3alpha-galactosyltransferase knock-out mice

21 January 2018

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Use of lentiviral vectors to induce long-term tolerance to gal(+) heart grafts

21 January 2018

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Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejection

21 January 2018

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T cell and B cell tolerance to GALalpha1,3GAL-expressing heart xenografts is achieved in alpha1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism

21 January 2018

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Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism

21 January 2018

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Knock out of alpha1,3-galactosyltransferase or expression of alpha1,2-fucosyltransferase further protects CD55- and CD59-expressing mouse hearts in an ex vivo model of xenograft rejection.

21 January 2018

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Characteristics of immunoglobulin gene usage of the xenoantibody binding to gal-alpha(1,3)gal target antigens in the gal knockout mouse

21 January 2018

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The x-ray structure of an anti-tumour antibody in complex with antigen

21 January 2018

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Solution structure of a trisaccharide-antibody complex: comparison of NMR measurements with a crystal structure

21 January 2018

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Germline antibody recognition of distinct carbohydrate epitopes

21 January 2018

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Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens

21 January 2018

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Three-dimensional structures of carbohydrate determinants of Lewis system antigens: implications for effective antibody targeting of cancer

21 January 2018

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Polymorphism in the human anti-pig natural antibody repertoire: implications for antigen-specific immunoadsorption

21 January 2018

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Differential recognition by proteins of alpha-galactosyl residues on endothelial cell surfaces

21 January 2018

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Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3galactosyltransferase knock out mice.

21 January 2018

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The structure of anti-Gal immunoglobulin genes in naïve and stimulated Gal knockout mice

21 January 2018

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The in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection

21 January 2018

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Specificity of xenoreactive anti-Gal alpha 1-3Gal IgM for alpha-galactosyl ligands

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Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B(4) and molecular basis for metal binding and monosaccharide specificity

21 January 2018

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Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Expression cloning of a new member of the ABO blood group glycosyltransferases, iGb3 synthase, that directs the synthesis of isoglobo-glycosphingolipids

21 January 2018

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Incorporation of long CDR3s into V domains: implications for the structural evolution of the antibody-combining site

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Docking of combinatorial peptide libraries into a broadly cross-reactive human IgM.

21 January 2018

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DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases

21 January 2018

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

21 January 2018

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Naturally acquired anti-alpha Gal antibodies in a murine allograft model similar to delayed xenograft rejection

21 January 2018

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7 January 2021

Hyperacute rejection of vascularized heart transplants in BALB/c Gal knockout mice

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7 January 2021

A murine model of antibody-mediated hyperacute rejection by galactose-alpha(1,3)galactose antibodies in Gal o/o mice

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7 January 2021

Anti-Gal antibody-mediated allograft rejection in alpha1,3-galactosyltransferase gene knockout mice: a model of delayed xenograft rejection

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7 January 2021

Fucosyl transferase (H) transgenic heart transplants to Gal-/- mice

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7 January 2021

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7 January 2021

The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study at 2.6-A resolution

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7 January 2021

Recognition of IgG-Derived Peptides by a Human IgM with an Unusual Combining Site

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7 January 2021

Pig cells that lack the gene for alpha1-3 galactosyltransferase express low levels of the gal antigen

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7 January 2021

Monoclonal antibodies that recognize the trisaccharide epitope Gal alpha 1-3Gal beta 1-4GlcNAc present on Ehrlich tumor cell membrane glycoproteins

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7 January 2021

Antibodies directed to pig non-Gal antigens in naïve and sensitized baboons

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7 January 2021

Elicited antibodies in baboons exposed to tissues from alpha1,3-galactosyltransferase gene-knockout pigs

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7 January 2021

Diverse binding site structures revealed in homology models of polyreactive immunoglobulins

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7 January 2021

Mcg light chain dimer as a model system for ligand design: a docking study

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7 January 2021