(Q38302676)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278498%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Dimeric fragment of the insulin receptor alpha-subunit binds insulin with full holoreceptor affinity (English)

1 reference

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6 November 2019

1 reference

3

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6 November 2019

author name string

Brandt J

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278498%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Andersen AS

series ordinal

2

1 reference

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6 November 2019

language of work or name

English

0 references

publication date

12 January 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278498%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 November 2019

published in

1 reference

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6 November 2019

volume

276

1 reference

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6 November 2019

issue

15

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6 November 2019

page(s)

12378-12384

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278498%20AND%20SRC:MED&resulttype=core&format=json

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

6 November 2019

cites work

1 reference

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Structure of the human insulin receptor gene and characterization of its promoter

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The insulin receptor: from protein sequence to structure.

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On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.

21 January 2018

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Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor

21 January 2018

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Identification of a disulfide bridge connecting the alpha-subunits of the extracellular domain of the insulin receptor

21 January 2018

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Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.

21 January 2018

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Changing the insulin receptor to possess insulin-like growth factor I ligand specificity

21 January 2018

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Properties of the insulin receptor ectodomain

21 January 2018

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The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling.

21 January 2018

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A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor

21 January 2018

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Fusion of insulin receptor ectodomains to immunoglobulin constant domains reproduces high-affinity insulin binding in vitro

21 January 2018

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High affinity insulin binding by soluble insulin receptor extracellular domain fused to a leucine zipper

21 January 2018

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Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding

21 January 2018

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Insulin binding changes the interface region between alpha subunits of the insulin receptor

21 January 2018

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Insulin interactions with its receptors: experimental evidence for negative cooperativity.

21 January 2018

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A region of the insulin receptor important for ligand binding (residues 450-601) is recognized by patients' autoimmune antibodies and inhibitory monoclonal antibodies

21 January 2018

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A model for the quaternary structure of human placental insulin receptor deduced from electron microscopy

21 January 2018

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Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor

21 January 2018

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Mechanism of transmembrane signaling: insulin binding and the insulin receptor

21 January 2018

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A third fibronectin-type-III domain in the insulin-family receptors

21 January 2018

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The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomain

21 January 2018

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Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor

21 January 2018

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A third fibronectin type III domain in the extracellular region of the insulin receptor family

21 January 2018

1 reference

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Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor alpha subunit

21 January 2018

1 reference

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Truncation of the ectodomain of the human insulin receptor results in secretion of a soluble insulin binding protein from transfected CHO cells

21 January 2018

1 reference

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A model for insulin binding to the insulin receptor

21 January 2018

1 reference

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Specificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunit

21 January 2018

1 reference

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Structural domains of the insulin receptor and IGF receptor required for dimerisation and ligand binding

21 January 2018

1 reference

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High affinity insulin binding in the human placenta insulin receptor requires alpha beta heterodimeric subunit interactions

21 January 2018

1 reference

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Quaternary structure of the insulin-insulin receptor complex

21 January 2018

1 reference

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Single-molecule imaging of human insulin receptor ectodomain and its Fab complexes

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M009402200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11278498%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference