(Q38303763)

English

DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): evidence for two major allozymes in extensive metabolisers

scientific article published on October 1994

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scholarly article

1 reference

Europe PubMed Central

1 September 2017

DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6): evidence for two major allozymes in extensive metabolisers (English)

1 reference

Europe PubMed Central

1 September 2017

Evelyne Jacqz-Aigrain

6

1 reference

Europe PubMed Central

1 September 2017

author name string

S Panserat

1

1 reference

Europe PubMed Central

1 September 2017

C Mura

2

1 reference

Europe PubMed Central

1 September 2017

N Gérard

3

1 reference

Europe PubMed Central

1 September 2017

M Vincent-Viry

4

1 reference

Europe PubMed Central

1 September 2017

M M Galteau

5

1 reference

Europe PubMed Central

1 September 2017

R Krishnamoorthy

7

1 reference

Europe PubMed Central

1 September 2017

publication date

1 October 1994

1 reference

Europe PubMed Central

1 September 2017

1 reference

Europe PubMed Central

1 September 2017

94

1 reference

Europe PubMed Central

1 September 2017

401-406

1 reference

Europe PubMed Central

1 September 2017

4

1 reference

Europe PubMed Central

1 September 2017

https://scigraph.springernature.com/pub.10.1007/bf00201601

0 references

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution crystal structure of cytochrome P450cam

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by the polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the CYP2D gene locus to human chromosome 22q13.1 by polymerase chain reaction, in situ hybridization, and linkage analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA haplotype dependency of debrisoquine 4-hydroxylase (CYP2D6) expression among extensive metabolisers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA sequencing with chain-terminating inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The debrisoquine metabolic phenotype and DNA-based assays: implications of misclassification for the association of lung cancer and the debrisoquine metabolic phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence in humans for variant allozymes of the nondeficient sparteine/debrisoquine monooxygenase (P45OIID 1) in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic differences in dextromethorphan metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutageneses of rat liver cytochrome P-450d: axial ligand and heme incorporation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant debrisoquine hydroxylation genes in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7927337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00201601

1 reference

Europe PubMed Central

1 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

1 September 2017

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