(Q38311693)

2 September 2017

Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene (English)

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2 September 2017

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Tomita-Mitchell A

1

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2 September 2017

Kat AG

2

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2 September 2017

Marcelino LA

3

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2 September 2017

Li-Sucholeiki XC

4

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2 September 2017

Goodluck-Griffith J

5

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2 September 2017

Thilly WG

6

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2 September 2017

language of work or name

English

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publication date

1 May 2000

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2 September 2017

14

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published in

Mutation Research

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2 September 2017

450

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2 September 2017

125-138

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2 September 2017

1-2

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INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL.

2 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA sequence analysis of the mutational specificity of u.v. light in the SUP4-o gene of yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Molecular analysis of complex human cell populations: mutational spectra of MNNG and ICR-191.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutational spectra vary with exposure conditions: benzo[a]pyrene in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mismatch correction at O 6 -methylguanine residues in E. coli DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutations of GTBP in genetically unstable cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: Possibility for a rapid human cell mutation assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mismatch repair defects and O6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

A statistical model to estimate variance in long term-low dose mutation assays: testing of the model in a human lymphoblastoid mutation assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Ultraviolet light-induced mutation of diploid human lymphoblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Constant denaturant capillary electrophoresis (CDCE): a high resolution approach to mutational analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutational spectrometry without phenotypic selection: human mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

A sensitive scanning technology for low frequency nuclear point mutations in human genomic DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Molecular analysis of mutations in mutator colorectal carcinoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Characterization of distinct human endometrial carcinoma cell lines deficient in mismatch repair that originated from a single tumor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

In vivo formation and persistence of modified nucleosides resulting from alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA alkylation repair and the induction of cell death and sister chromatid exchange in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Alkylation damage, DNA repair and mutagenesis in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Influence of neighbouring base sequence on N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the lacI gene of Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Novel mutational spectrum induced by N-methyl-N'-nitro-N-nitrosoguanidine in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Site-directed mutagenesis for quantitation of base-base interactions at defined sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mechanisms of chemical mutagenesis and carcinogenesis: effects on DNA replication of methylation at the O6-guanine position of dGTP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutagenesis by apurinic/apyrimidinic sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutational specificity of depurination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Effect of the direction of DNA replication on mutagenesis by N-methyl-N'-nitro-N-nitrosoguanidine in adapted cells of Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Role of neighbouring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the SUP4-o gene of Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

N-methyl-N'-nitro-N-nitrosoguanidine induced DNA sequence alteration; non-random components in alkylation mutagenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutational specificity of alkylating agents and the influence of DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900020-8

10.1016/S0027-5107(00)00020-8

7 January 2021

Identifiers

DOI

1 reference

2 September 2017

1 reference