(Q38313567)

2 September 2017

title

A novel repressor domain is required for maximal growth inhibition by the IRF-1 tumor suppressor (English)

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2 September 2017

Mirjam Eckert

1

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2 September 2017

Sarah E M Meek

series ordinal

2

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2 September 2017

Kathryn L Ball

series ordinal

3

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2 September 2017

language of work or name

English

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publication date

4 May 2006

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

281

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2 September 2017

issue

32

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2 September 2017

page(s)

23092-23102

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IRF family of transcription factors as regulators of host defense

2 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M512589200

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Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway

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Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53

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The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter

21 January 2018

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Identification of the secretory leukocyte protease inhibitor (SLPI) as a target of IRF-1 regulation

21 January 2018

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Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

21 January 2018

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IRF-1 reverts the transformed phenotype of oncogenically transformed cells in vitro and in vivo

21 January 2018

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Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia

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Common deleted region on the long arm of chromosome 5 in esophageal carcinoma.

21 January 2018

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Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53.

21 January 2018

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Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes.

21 January 2018

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Structure of IRF-1 with bound DNA reveals determinants of interferon regulation

21 January 2018

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21 January 2018

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Functional dissection of the transactivation domain of interferon regulatory factor-1

21 January 2018

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Interplay between repressing and activating domains defines the transcriptional activity of IRF-1.

21 January 2018

1 reference

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Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription

21 January 2018

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Activation of multiple growth regulatory genes following inducible expression of IRF-1 or IRF/RelA fusion proteins

21 January 2018

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Tumor suppressor IRF-1 mediates retinoid and interferon anticancer signaling to death ligand TRAIL

21 January 2018

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The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

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A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both interferon type I and type II.

21 January 2018

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Degradation of transcription factor IRF-1 by the ubiquitin-proteasome pathway. The C-terminal region governs the protein stability

21 January 2018

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Induction of endogenous IFN-alpha and IFN-beta genes by a regulatory transcription factor, IRF-1.

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The coactivator LXXLL nuclear receptor recognition motif.

21 January 2018

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Structure and specificity of nuclear receptor-coactivator interactions

21 January 2018

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

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SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation

21 January 2018

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A transcriptional corepressor of Stat1 with an essential LXXLL signature motif

21 January 2018

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Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

21 January 2018

1 reference

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Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

21 January 2018

1 reference

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An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

21 January 2018

1 reference

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Activation and repression of the 2-5A synthetase and p21 gene promoters by IRF-1 and IRF-2

21 January 2018

1 reference

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In vivo formation of IRF-1 homodimers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M512589200

1 reference

2 September 2017

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