(Q38313605)

English

Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter

scientific article published on June 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

1 reference

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author name string

Steer JH

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Kroeger KM

2

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Abraham LJ

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Joyce DA

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

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publication date

1 June 2000

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Europe PubMed Central

PubMed publication ID

2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

2 September 2017

275

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Europe PubMed Central

PubMed publication ID

2 September 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

18432-18440

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

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A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

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21 January 2018

Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors

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21 January 2018

C/EBP beta regulation of the tumor necrosis factor alpha gene

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21 January 2018

Cytomegalovirus modulates transcription factors necessary for the activation of the tumor necrosis factor-alpha promoter.

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Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK.

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21 January 2018

Relative contribution of transcription and translation to the induction of tumor necrosis factor-alpha by lipopolysaccharide

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21 January 2018

Glucocorticoid modulation of human monocyte/macrophage function: control of TNF-alpha secretion

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Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.

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Granulocyte-macrophage colony-stimulating factor and interleukin-4 differentially regulate the human tumor necrosis factor-alpha promoter region

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Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

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Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

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Regulation of the human TNF promoter by the transcription factor Ets.

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Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

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CD14 is a pattern recognition receptor

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Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway

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The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription.

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21 January 2018

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

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Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

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An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcriptional activators

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Identification of a cyclic-AMP-responsive element within the rat somatostatin gene

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Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

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21 January 2018

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

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21 January 2018

Dexamethasone antagonizes IL-4 and IL-10-induced release of IL-1RA by monocytes but augments IL-4-, IL-10-, and TGF-beta-induced suppression of TNF-alpha release

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21 January 2018

Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun

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21 January 2018

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

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21 January 2018

Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

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21 January 2018

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

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21 January 2018

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

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21 January 2018

Dexamethasone attenuates NF-kappa B DNA binding activity without inducing I kappa B levels in rat brain in vivo

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21 January 2018

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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21 January 2018

Ischemia and reperfusion enhance ATF-2 and c-Jun binding to cAMP response elements and to an AP-1 binding site from the c-jun promoter

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21 January 2018

Glucocorticoid receptor mRNA expression in pulmonary alveolar macrophages in sarcoidosis

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Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

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Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

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Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

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Cooperativity between two NF-kappa B complexes, mediated by high-mobility-group protein I(Y), is essential for cytokine-induced expression of the E-selectin promoter

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Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide

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Preparation and characterization of monoclonal antibodies directed against antigenic determinants of recombinant human tumour necrosis factor (rTNF)

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Identifiers

10.1074/JBC.M906304199

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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