(Q38313997)

2 September 2017

title

NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events (English)

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2 September 2017

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T T Huang

1

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2 September 2017

S M Wuerzberger-Davis

2

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2 September 2017

B J Seufzer

3

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2 September 2017

S D Shumway

4

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2 September 2017

T Kurama

5

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2 September 2017

D A Boothman

6

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2 September 2017

S Miyamoto

7

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2 September 2017

language of work or name

English

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publication date

1 March 2000

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

275

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2 September 2017

issue

13

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2 September 2017

page(s)

9501-9509

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NF-kappa B: ten years after

2 September 2017

cites work

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Rel/NF-kappa B transcription factors and the control of apoptosis

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

21 January 2018

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Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV

21 January 2018

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Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

21 January 2018

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Calpain contributes to silica-induced IkB-a degradation and nuclear factor-kB activation

21 January 2018

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Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells

21 January 2018

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NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

21 January 2018

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

21 January 2018

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UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins

21 January 2018

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DNA topoisomerase poisons as antitumor drugs

21 January 2018

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The current status of camptothecin analogues as antitumor agents

21 January 2018

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Topoisomerase I inhibitors: review and update

21 January 2018

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Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells

21 January 2018

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Enucleation of mammalian cells by cytochalasin B. I. Characterization of anucleate cells.

21 January 2018

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TRAF6 is a signal transducer for interleukin-1

21 January 2018

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Autoregulation of I kappa B alpha activity

21 January 2018

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Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

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Response of purified mitochondrial DNA topoisomerase I from bovine liver to camptothecin and m-AMSA.

21 January 2018

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

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Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

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MEK kinase is involved in tumor necrosis factor alpha-induced NF-kappaB activation and degradation of IkappaB-alpha.

21 January 2018

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

21 January 2018

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

21 January 2018

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Involvement of CRAF1, a relative of TRAF, in CD40 signaling

21 January 2018

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TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation

21 January 2018

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Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

21 January 2018

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

21 January 2018

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21 January 2018

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Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

The ATM protein is required for sustained activation of NF-kappaB following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9501

21 January 2018

Identifiers

DOI

10.1074/JBC.275.13.9501

1 reference

release_ug547xv3i5hhthfegxckorc5ca

2 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ug547xv3i5hhthfegxckorc5ca

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference