(Q38314625)

2 September 2017

title

Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours (English)

1 reference

2 September 2017

Friedman E

1

1 reference

2 September 2017

Gejman PV

series ordinal

2

1 reference

2 September 2017

Martin GA

series ordinal

3

1 reference

2 September 2017

McCormick F

series ordinal

4

1 reference

2 September 2017

language of work or name

English

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publication date

1 November 1993

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2 September 2017

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2 September 2017

volume

5

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2 September 2017

issue

3

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2 September 2017

page(s)

242-247

1 reference

https://scigraph.springernature.com/pub.10.1038/ng1193-242

2 September 2017

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

The neurofibromatosis type 1 gene encodes a protein related to GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Biochemical and biological properties of the human N-ras p21 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

In yeast, RAS proteins are controlling elements of adenylate cyclase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Genetic analysis of mammalian GAP expressed in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Somatic mutations in the neurofibromatosis 1 gene in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Signalling through SH2 and SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

PCR Amplification from Paraffin-Embedded Tissues: Effects of Fixative and Fixation Time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

[31] Detection and localization of single base changes by denaturing gradient gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

GTPase-activating protein interactions with the viral and cellular Src kinases

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

The approaching era of the tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Detection of Mutations in Insulin Receptor Gene by Denaturing Gradient Gel Electrophoresis

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Biology of basal cell carcinoma (Part I).

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Recent advances in the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Ras gene mutation and amplification in human nonmelanoma skin cancers

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Deletion of the c-Ha-ras-1 allele in human skin cancers

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Epidermal growth factor receptors in human epidermal tumours

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Isolation of high-molecular-weight DNA from mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

A rapid method for the purification of DNA from blood

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Sequence-Determined DNA Separations

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Direct sequencing of affinity-captured amplified human DNA application to the detection of apolipoprotein E polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FNG1193-242

7 January 2021

Identifiers

DOI

10.1038/NG1193-242

1 reference

2 September 2017

1 reference