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English
Galectin-9 regulates T helper cell function independently of Tim-3.
scientific article published on 27 December 2010
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Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
title
Galectin-9 regulates T helper cell function independently of Tim-3
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
main subject
cell function
0 references
author
Lawrence P. Kane
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author name string
Ee W Su
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Shuguang Bi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
publication date
27 December 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
published in
Glycobiology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
volume
21
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
issue
10
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
page(s)
1258-1265
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
cites work
Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Galectins: regulators of acute and chronic inflammation
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PubMed Central
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6 September 2017
T-bet, a Th1 transcription factor regulates the expression of Tim-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
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PubMed Central
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6 September 2017
Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators
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PubMed Central
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6 September 2017
Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Lack of TIM-3 immunoregulation in multiple sclerosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
retrieved
6 September 2017
T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Galectin-9 in physiological and pathological conditions
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
A novel transcription factor, T-bet, directs Th1 lineage commitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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6 September 2017
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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14 September 2017
A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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14 September 2017
Regulation of galectin-9 expression and release in Jurkat T cell line cells.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
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27 September 2017
CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
retrieved
27 September 2017
Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
retrieved
31 August 2018
Development of highly stable galectins: truncation of the linker peptide confers protease-resistance on tandem-repeat type galectins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
retrieved
31 August 2018
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3167474
retrieved
31 August 2018
Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21187321
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21187321
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/GLYCOB/CWQ214
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PMC publication ID
3167474
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed publication ID
21187321
1 reference
stated in
Europe PubMed Central
PMC publication ID
3167474
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21187321%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ResearchGate publication ID
49710817
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