(Q38317155)

2 September 2017

Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis (English)

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2 September 2017

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Gårdsvoll H

1

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2 September 2017

Danø K

series ordinal

2

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2 September 2017

Ploug M

series ordinal

3

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2 September 2017

language of work or name

English

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publication date

1 December 1999

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Journal of Biological Chemistry

2 September 2017

9

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based on heuristic

inferred from page(s)

published in

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2 September 2017

274

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2 September 2017

37995-38003

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2 September 2017

53

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describes a project that uses

2 September 2017

site-directed mutagenesis

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based on heuristic

inferred from title

cites work

Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Prevention of metastasis by inhibition of the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Cloning and functional characterization of a new phosphatidyl-inositol anchored molecule of a metastasizing rat pancreatic tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Functional architectures of animal toxins: a clue to drug design?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Crystal structure of kappa-bungarotoxin at 2.3-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

A hot spot of binding energy in a hormone-receptor interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Anatomy of hot spots in protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

A rapid and efficient one-tube PCR-based mutagenesis technique using Pfu DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Principles of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Thermodynamic analysis of an antibody functional epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Differential roles for disulfide bonds in the structural integrity and biological activity of kappa-Bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

The urokinase-type plasminogen activator system in cancer metastasis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

The two subunits of a phospholipase A2 inhibitor from the plasma of Thailand cobra having structural similarity to urokinase-type plasminogen activator receptor and LY-6 related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Photoaffinity labeling of the human receptor for urokinase-type plasminogen activator using a decapeptide antagonist. Evidence for a composite ligand-binding site and a short interdomain separation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Urokinase receptor in breast cancer tissue extracts. Enzyme-linked immunosorbent assay with a combination of mono- and polyclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Quantitation of the receptor for urokinase plasminogen activator by enzyme-linked immunosorbent assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Comparison of a structural and a functional epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Structure-function relationships of the complement regulatory protein, CD59

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Urokinase receptor antagonists: discovery and application to in vivo models of tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

Different mechanisms are involved in the antibody mediated inhibition of ligand binding to the urokinase receptor: a study based on biosensor technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.53.37995

21 January 2018

Identifiers

DOI

10.1074/JBC.274.53.37995

1 reference

2 September 2017

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ResearchGate publication ID

2 September 2017

51355103

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