(Q38317335)

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Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

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scholarly article

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Europe PubMed Central

2 September 2017

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart (English)

1 reference

Europe PubMed Central

2 September 2017

author name string

Wenjun Yan

1

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Europe PubMed Central

2 September 2017

Haifeng Zhang

2

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Europe PubMed Central

2 September 2017

Peilin Liu

3

1 reference

Europe PubMed Central

2 September 2017

Han Wang

4

1 reference

Europe PubMed Central

2 September 2017

Jingyi Liu

5

1 reference

Europe PubMed Central

2 September 2017

Chao Gao

6

1 reference

Europe PubMed Central

2 September 2017

Yi Liu

7

1 reference

Europe PubMed Central

2 September 2017

Kun Lian

8

1 reference

Europe PubMed Central

2 September 2017

Lu Yang

9

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Europe PubMed Central

2 September 2017

Lu Sun

10

1 reference

Europe PubMed Central

2 September 2017

Yunping Guo

11

1 reference

Europe PubMed Central

2 September 2017

Lijian Zhang

12

1 reference

Europe PubMed Central

2 September 2017

Ling Dong

13

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Europe PubMed Central

2 September 2017

Wayne Bond Lau

14

1 reference

Europe PubMed Central

2 September 2017

Erhe Gao

15

1 reference

Europe PubMed Central

2 September 2017

Feng Gao

16

1 reference

Europe PubMed Central

2 September 2017

Lize Xiong

17

1 reference

Europe PubMed Central

2 September 2017

Haichang Wang

18

1 reference

Europe PubMed Central

2 September 2017

Yan Qu

19

1 reference

Europe PubMed Central

2 September 2017

Ling Tao

20

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Europe PubMed Central

2 September 2017

publication date

5 March 2013

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Europe PubMed Central

2 September 2017

Basic Research in Cardiology

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Europe PubMed Central

2 September 2017

108

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Europe PubMed Central

2 September 2017

3

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Europe PubMed Central

2 September 2017

329

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Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1007/s00395-013-0329-1

0 references

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Mitochondria in the diabetic heart

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https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Role of adiponectin in human skeletal muscle bioenergetics

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of Type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Mitochondrial energy metabolism in heart failure: a question of balance

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Full-length adiponectin protects hepatocytes from palmitate-induced apoptosis via inhibition of c-Jun NH2 terminal kinase.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Diabetes and cardiovascular disease. The Framingham study

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin inhibits palmitate-induced apoptosis through suppression of reactive oxygen species in endothelial cells: involvement of cAMP/protein kinase A and AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin and development of type 2 diabetes in the Pima Indian population

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Implications of plasma concentrations of adiponectin in patients with coronary artery disease

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Cardioprotection by adiponectin

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Plasma adiponectin levels and risk of myocardial infarction in men.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin: an indispensable molecule in rosiglitazone cardioprotection following myocardial infarction

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Mitochondrial dysfunction in cardiac ischemia-reperfusion injury: ROS from complex I, without inhibition.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha.

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Rosiglitazone treatment in Zucker diabetic Fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

1 reference

https://api.crossref.org/works/10.1007%2FS00395-013-0329-1

21 January 2018

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10.1007/S00395-013-0329-1

1 reference

Europe PubMed Central

2 September 2017

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1 reference

Europe PubMed Central

2 September 2017

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