(Q38317861)

English

Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation.

scientific article published in December 1999

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scholarly article

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2 November 2019

Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation (English)

1 reference

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2 November 2019

2

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2 November 2019

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B M Shewchuk

1

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2 November 2019

N E Cooke

3

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2 November 2019

S A Liebhaber

4

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2 November 2019

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1 December 1999

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2 November 2019

Journal of Biological Chemistry

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2 November 2019

274

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2 November 2019

35725-35733

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2 November 2019

50

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2 November 2019

Transcriptional activation: a complex puzzle with few easy pieces

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

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21 January 2018

Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Silencers and locus control regions: opposite sides of the same coin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone

1 reference

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21 January 2018

Cytological localization of placental lactogen messenger ribonucleic acid in syncytiotrophoblast layers of human placenta

1 reference

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21 January 2018

Characterization and histologic localization of human growth hormone-variant gene expression in the placenta

1 reference

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21 January 2018

The human growth hormone gene is regulated by a multicomponent locus control region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

GHF-1-promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice

1 reference

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21 January 2018

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1 reference

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21 January 2018

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1 reference

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21 January 2018

57 Sequencing end-labeled DNA with base-specific chemical cleavages

1 reference

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21 January 2018

The human growth hormone locus: nucleotide sequence, biology, and evolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Rat Pit-1 stimulates transcription in vitro by influencing pre-initiation complex assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Dissection of functional domains of the pituitary-specific transcription factor GHF-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Transcriptional activation by recruitment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene

1 reference

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21 January 2018

Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

A two-base change in a POU factor-binding site switches pituitary-specific to lymphoid-specific gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

The molecular biology of axon guidance

1 reference

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21 January 2018

Enhancers increase the probability but not the level of gene expression

1 reference

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21 January 2018

Position effect variegation in Drosophila: towards a genetics of chromatin assembly

1 reference

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21 January 2018

Position-effect variegation after 60 years

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

Signal-specific co-activator domain requirements for Pit-1 activation

1 reference

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21 January 2018

Histone acetylation: chromatin in action

1 reference

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21 January 2018

Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.

1 reference

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21 January 2018

Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene.

1 reference

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21 January 2018

Developmental regulation of a cloned adult β-globin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.50.35725

21 January 2018

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