(Q38318487)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

M J Calonge

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 November 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

33637-33643

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

Lessons from hereditary colorectal cancer

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Genomic sequencing of DPC4 in the analysis of familial pancreatic carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Evidence for c-myc in the signaling pathway for TGF-beta in well-differentiated human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Cell cycle targets of Ras/Raf signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

Prevalence of ras gene mutations in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.47.33637

21 January 2018

Identifiers

DOI

10.1074/JBC.274.47.33637

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559252%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference