(Q38320544)

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New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity

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Europe PubMed Central

2 September 2017

New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity (English)

1 reference

Europe PubMed Central

2 September 2017

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author name string

Kim B

1

1 reference

Europe PubMed Central

2 September 2017

Ayran JC

2

1 reference

Europe PubMed Central

2 September 2017

Sagar SG

3

1 reference

Europe PubMed Central

2 September 2017

Adman ET

4

1 reference

Europe PubMed Central

2 September 2017

Fuller SM

5

1 reference

Europe PubMed Central

2 September 2017

Tran NH

6

1 reference

Europe PubMed Central

2 September 2017

Horrigan J

7

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Europe PubMed Central

2 September 2017

language of work or name

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publication date

1 September 1999

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Europe PubMed Central

2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

2 September 2017

274

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2 September 2017

27666-27673

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Europe PubMed Central

2 September 2017

39

1 reference

Europe PubMed Central

2 September 2017

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Mechanisms of retroviral mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Strand transfer mediated by human immunodeficiency virus reverse transcriptase in vitro is promoted by pausing and results in misincorporation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Function and structure relationships in DNA polymerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Polymerase structures and function: variations on a theme?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Lamivudine resistance of HIV type 1 does not delay development of resistance to nonnucleoside HIV type 1-specific reverse transcriptase inhibitors as compared with wild-type HIV type 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Genetic selection in Escherichia coli for active human immunodeficiency virus reverse transcriptase mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Dominance of the E89G substitution in HIV-1 reverse transcriptase in regard to increased polymerase processivity and patterns of pausing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Analyzing fidelity of DNA polymerases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

HIV genetic variation is directed and restricted by DNA precursor availability.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

A new type of G-->A hypermutation affecting human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Misincorporation by HIV-1 reverse transcriptase promotes recombination via strand transfer synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27666

21 January 2018

Identifiers

10.1074/JBC.274.39.27666

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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