(Q38325277)

2 September 2017

Tumor-associated WT1 missense mutants indicate that transcriptional activation by WT1 is critical for growth control (English)

1 reference

2 September 2017

English MA

1

1 reference

PubMed ID

10224085

2 September 2017

Licht JD

series ordinal

2

1 reference

PubMed ID

10224085

2 September 2017

language of work or name

English

0 references

publication date

1 May 1999

1 reference

Journal of Biological Chemistry

2 September 2017

1 reference

2 September 2017

274

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2 September 2017

19

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2 September 2017

13258-13263

1 reference

New developments in the pathology of Wilms tumor

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

A clinical overview of WT1 gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Alternative splicing and genomic structure of the Wilms tumor gene WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Transcriptional repression mediated by the WT1 Wilms tumor gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

A second transcriptionally active DNA-binding site for the Wilms tumor gene product, WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

High affinity binding sites for the Wilms' tumour suppressor protein WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The genomic organization and expression of the WT1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Repression of the c-myb gene by WT1 protein in T and B cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The genetics of Wilms' tumor--a case of disrupted development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Antagonism of WT1 activity by protein self-association.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N'-methylurea

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The transcriptional effect of WT1 is modulated by choice of expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The regulation of IGF-I receptor gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Analysis of WT1 target gene expression in stably transfected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

RNA binding by the Wilms tumor suppressor zinc finger proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Langer-Giedion syndrome and deletion of the long arm of chromosome 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Autoregulation of the human WT1 gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Evidence that WT1 mutations in Denys — Drash syndrome patients may act in a dominant-negative fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

A novel insertional mutation at the third zinc finger coding region of the WT1 gene in Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.19.13258

21 January 2018

Identifiers

DOI

10.1074/JBC.274.19.13258

1 reference

2 September 2017

1 reference

PubMed ID

10224085