(Q38330766)

2 September 2017

title

Cysteines in CH1 underlie retention of unassembled Ig heavy chains (English)

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2 September 2017

Yechiel Elkabetz

1

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2 September 2017

Yair Argon

series ordinal

2

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2 September 2017

Shoshana Bar-Nun

series ordinal

3

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2 September 2017

language of work or name

English

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publication date

10 February 2005

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

280

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2 September 2017

issue

15

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2 September 2017

page(s)

14402-14412

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Three-Dimensional Structure of Immunoglobulins

2 September 2017

cites work

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Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release

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Immunoglobulin heavy chain binding protein

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Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas

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Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition

21 January 2018

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Coordination of immunoglobulin chain folding and immunoglobulin chain assembly is essential for the formation of functional IgG.

21 January 2018

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Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

21 January 2018

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The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP.

21 January 2018

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The in vivo association of BiP with newly synthesized proteins is dependent on the rate and stability of folding and not simply on the presence of sequences that can bind to BiP.

21 January 2018

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Enhanced transcription of the 78,000-dalton glucose-regulated protein (GRP78) gene and association of GRP78 with immunoglobulin light chains in a nonsecreting B-cell myeloma line (NS-1).

21 January 2018

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A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion

21 January 2018

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Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding

21 January 2018

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Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity

21 January 2018

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BiP binding sequences in antibodies.

21 January 2018

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BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly

21 January 2018

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Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine

21 January 2018

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Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents

21 January 2018

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Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination

21 January 2018

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Immunoglobulin Light Chains Dictate Vesicular Transport-dependent and -independent Routes for IgM Degradation by the Ubiquitin-Proteasome Pathway

21 January 2018

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Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.

21 January 2018

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Crystal structure to 2.45 A resolution of a monoclonal Fab specific for the Brucella A cell wall polysaccharide antigen

21 January 2018

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X-ray crystallography reveals stringent conservation of protein fold after removal of the only disulfide bridge from a stabilized immunoglobulin variable domain

21 January 2018

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Contribution of the intramolecular disulfide bridge to the folding stability of REIv, the variable domain of a human immunoglobulin kappa light chain.

21 January 2018

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Interaction of the thiol-dependent reductase ERp57 with nascent glycoproteins

21 January 2018

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ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family

21 January 2018

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Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44

21 January 2018

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Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum

21 January 2018

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BiP and PDI cooperate in the oxidative folding of antibodies in vitro

21 January 2018

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Quality control in the endoplasmic reticulum: PDI mediates the ER retention of unassembled procollagen C-propeptides

21 January 2018

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Protein folding and quality control in the endoplasmic reticulum

21 January 2018

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Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex

21 January 2018

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ERp19 and ERp46, new members of the thioredoxin family of endoplasmic reticulum proteins

21 January 2018

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Expression of an active Na,K-ATPase with an alpha-subunit lacking all twenty-three native cysteine residues

21 January 2018

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Disulfide bond in Pseudomonas aeruginosa lipase stabilizes the structure but is not required for interaction with its foldase

21 January 2018

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The disulfide bond in the Aeromonas hydrophila lipase/acyltransferase stabilizes the structure but is not required for secretion or activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500161200

Mutant (delta F508) cystic fibrosis transmembrane conductance regulator Cl- channel is functional when retained in endoplasmic reticulum of mammalian cells.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M500161200

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2 September 2017

1 reference