(Q38330800)

2 September 2017

Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase (English)

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2 September 2017

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1 reference

Harris D

1

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2 September 2017

Kaushik N

2

1 reference

2 September 2017

Pandey PK

3

1 reference

2 September 2017

Yadav PN

4

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2 September 2017

Pandey VN

5

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2 September 2017

language of work or name

English

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publication date

1 December 1998

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

273

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2 September 2017

33624-33634

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2 September 2017

50

1 reference

Viral dynamics in human immunodeficiency virus type 1 infection

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

The accuracy of reverse transcriptase from HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

An attempt to unify the structure of polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Elucidation of the role of Arg 110 of murine leukemia virus reverse transcriptase in the catalytic mechanism: biochemical characterization of its mutant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

DNA sequencing with chain-terminating inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

An enzymatically active chimeric HIV-1 reverse transcriptase (RT) with the RNase-H domain of murine leukemia virus RT exists as a monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Significance of the O-helix residues of Escherichia coli DNA polymerase I in DNA synthesis: dynamics of the dNTP binding pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Chromosomal aberrations and sister-chromatid exchanges in lymphocytes from coke oven workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

RNA dependent DNA replication fidelity of HIV-1 reverse transcriptase: evidence of discrimination between DNA and RNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Site-specific mutagenesis of AIDS virus reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Fidelity of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Rate-limiting steps in the DNA polymerase I reaction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Kinetic mechanism of DNA polymerase I (Klenow).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Insertions into the β3-β4 Hairpin Loop of HIV-1 Reverse Transcriptase Reveal a Role for Fingers Subdomain in Processive Polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Glutamine 151 participates in the substrate dNTP binding function of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Kinetic analysis of template.primer interactions with recombinant forms of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.50.33624

21 January 2018

Identifiers

DOI

10.1074/JBC.273.50.33624

1 reference

2 September 2017

1 reference