(Q38331876)

2 September 2017

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title

Overview: neurobiology of OB protein (leptin). (English)

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2 September 2017

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Campfield LA

1

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2 September 2017

Smith FJ

series ordinal

2

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2 September 2017

publication date

1 August 1998

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Proceedings of the Nutrition Society

2 September 2017

published in

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2 September 2017

volume

57

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2 September 2017

issue

3

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2 September 2017

page(s)

429-440

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The OB protein (leptin) pathway--a link between adipose tissue mass and central neural networks

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Changes in Energy Expenditure Resulting from Altered Body Weight

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Positional cloning of the mouse obese gene and its human homologue

21 January 2018

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Abnormal splicing of the leptin receptor in diabetic mice

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The role of depot fat in the hypothalamic control of food intake in the rat.

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Leptin and OB-R: body weight regulation by a cytokine receptor

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Metabolic factors in the control of energy stores

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Intracerebroventricular injection of leptin increases thermogenesis and mobilizes fat metabolism in ob/ob mice

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Leptin enters the brain by a saturable system independent of insulin

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Physiological mechanisms for the regulation of energy balance

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Role of leptin in the neuroendocrine response to fasting

21 January 2018

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Identification and expression cloning of a leptin receptor, OB-R

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Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

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The role of neuropeptide Y in the antiobesity action of the obese gene product

21 January 2018

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Defective STAT signaling by the leptin receptor in diabetic mice

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Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

21 January 2018

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

21 January 2018

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Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

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OB protein binds specifically to the choroid plexus of mice and rats

21 January 2018

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Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats.

21 January 2018

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

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The influence of genetic background on the expression of the obese (ob) gene in the mouse

21 January 2018

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Identification of targets of leptin action in rat hypothalamus

21 January 2018

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21 January 2018

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21 January 2018

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Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats

21 January 2018

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Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

21 January 2018

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

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Obesity, leptin, and the brain.

21 January 2018

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Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

21 January 2018

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The loop system between neuropeptide Y and leptin in normal and obese rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

21 January 2018

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

21 January 2018

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https://api.crossref.org/works/10.1079%2FPNS19980062

Human eating: evidence for a physiological basis using a modified paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS19980062

21 January 2018

Identifiers

DOI

10.1079/PNS19980062

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2 September 2017

1 reference