(Q38332622)

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Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver

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scholarly article

1 reference

Europe PubMed Central

2 September 2017

Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver (English)

1 reference

Europe PubMed Central

2 September 2017

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1 reference

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author name string

A Lieber

1

1 reference

Europe PubMed Central

2 September 2017

C Y He

2

1 reference

Europe PubMed Central

2 September 2017

L Meuse

3

1 reference

Europe PubMed Central

2 September 2017

C Himeda

4

1 reference

Europe PubMed Central

2 September 2017

C Wilson

5

1 reference

Europe PubMed Central

2 September 2017

M A Kay

6

1 reference

Europe PubMed Central

2 September 2017

language of work or name

0 references

publication date

1 November 1998

1 reference

Europe PubMed Central

2 September 2017

Journal of Virology

1 reference

Europe PubMed Central

2 September 2017

72

1 reference

Europe PubMed Central

2 September 2017

9267-9277

1 reference

Europe PubMed Central

2 September 2017

11

1 reference

Europe PubMed Central

2 September 2017

Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

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The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors.

1 reference

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The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis

1 reference

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6 September 2017

Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors

1 reference

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6 September 2017

Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

1 reference

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6 September 2017

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Regulation of apoptosis by viral gene products

1 reference

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Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers

1 reference

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6 September 2017

Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo

1 reference

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6 September 2017

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

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6 September 2017

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

NF-kappa B: ten years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

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6 September 2017

The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection

1 reference

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Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes

1 reference

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Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

1 reference

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6 September 2017

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

6 September 2017

Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

14 September 2017

bcl-2 acts early to restrict Semliki Forest virus replication and delays virus-induced programmed cell death

1 reference

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Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules

1 reference

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Regulation of TNF-mediated cell death and inflammation by human adenoviruses.

1 reference

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Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

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Tumor necrosis factor alpha induces the adenovirus early 3 promoter by activation of NF-kappaB.

1 reference

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Adenovirus-mediated hepatic gene transfer in mice: comparison of intravascular and biliary administration

1 reference

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Apoptosis and chemotherapy resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

27 September 2017

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

1 reference

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27 September 2017

Current status of CF gene therapy

1 reference

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27 September 2017

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

1 reference

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27 September 2017

293 cell lines that inducibly express high levels of adenovirus type 5 precursor terminal protein

1 reference

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27 September 2017

High adenoviral loads stimulate NF kappaB-dependent gene expression in human vascular smooth muscle cells

1 reference

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23 June 2018

NF-kappaB activation: the I kappaB kinase revealed?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

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The role of Rel/NF-kappa B proteins in viral oncogenesis and the regulation of viral transcription

1 reference

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23 June 2018

Rel/NF-kappa B transcription factors and the control of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

23 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

23 June 2018

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1 reference

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23 June 2018

Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

23 June 2018

Human adenovirus vectors for gene transfer into mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

23 June 2018

Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

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The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

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23 June 2018

Tumor necrosis factors in 1996.

1 reference

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23 June 2018

Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110346

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Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation

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Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

1 reference

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Constitutive expression of murine CTLA4Ig from a recombinant adenovirus vector results in prolonged transgene expression

1 reference

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Method for multiple portal vein infusions in mice: quantitation of adenovirus-mediated hepatic gene transfer.

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CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

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DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309.

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Introduction: The Rel/NF-kappaB signal transduction pathway

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Expression and release of the latent transforming growth factor beta binding protein by hepatocytes from rat liver

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Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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