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The two steps of group II intron self-splicing are mechanistically distinguishable.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
title
The two steps of group II intron self-splicing are mechanistically distinguishable
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
author
Mircea Podar
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
Richard A Padgett
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
author name string
P S Perlman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
language of work or name
English
0 references
publication date
1 August 1998
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
published in
RNA
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
volume
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
page(s)
890-900
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
cites work
Group II intron ribozymes that cleave DNA and RNA linkages with similar efficiency, and lack contacts with substrate 2'-hydroxyl groups
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing
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PubMed Central
reference URL
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6 September 2017
A general two-metal-ion mechanism for catalytic RNA
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PubMed Central
reference URL
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6 September 2017
Conversion of a group II intron into a new multiple-turnover ribozyme that selectively cleaves oligonucleotides: elucidation of reaction mechanism and structure/function relationships
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
1 reference
stated in
PubMed Central
reference URL
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6 September 2017
Structure and activities of group II introns
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5'-splice site selection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Stability constants of magnesium and cadmium complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of magnesium-ATP and magnesium-ADP
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PubMed Central
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6 September 2017
A proton-coupled conformational switch of Escherichia coli 5S ribosomal RNA
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PubMed Central
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6 September 2017
Stereochemical course of catalysis by the Tetrahymena ribozyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Nucleoside phosphorothioates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
6 September 2017
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
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6 September 2017
Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
6 September 2017
A phosphorothioate at the 3' splice-site inhibits the second splicing step in a group I intron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
6 September 2017
The stereochemical course of the first step of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
14 September 2017
Stereochemical selectivity of group II intron splicing, reverse splicing, and hydrolysis reactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
14 September 2017
Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
14 September 2017
An RNA conformational change between the two chemical steps of group II self-splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
27 September 2017
Group II introns: elaborate ribozymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
27 September 2017
Ribozyme catalysis from the major groove of group II intron domain 5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
The stereochemical course of group II intron self-splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
Role of divalent metal ions in the hammerhead RNA cleavage reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
23 June 2018
pH dependencies of the Tetrahymena ribozyme reveal an unconventional origin of an apparent pKa.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
31 August 2018
Comparison of pH dependencies of the Tetrahymena ribozyme reactions with RNA 2'-substituted and phosphorothioate substrates reveals a rate-limiting conformational step
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
31 August 2018
Solution conformation of an RNA hairpin loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
31 August 2018
Metal ion catalysis during splicing of premessenger RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369667
retrieved
3 December 2018
Multiple magnesium ions in the ribonuclease P reaction mechanism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9701281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Catalytic site components common to both splicing steps of a group II intron
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9701281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Group II intron self-splicing. Alternative reaction conditions yield novel products
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9701281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Two competing pathways for self-splicing by group II introns: a quantitative analysis of in vitro reaction rates and products
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9701281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1017/S1355838298971643
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
PMC publication ID
1369667
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
PubMed publication ID
9701281
1 reference
stated in
Europe PubMed Central
PMC publication ID
1369667
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9701281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
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