(Q38337652)

2 September 2017

Fluconazole binding and sterol demethylation in three CYP51 isoforms indicate differences in active site topology (English)

1 reference

2 September 2017

1 reference

Aouatef Bellamine

1

1 reference

PubMed ID

15314102

2 September 2017

Galina I Lepesheva

series ordinal

2

1 reference

PubMed ID

15314102

2 September 2017

Michael R Waterman

series ordinal

3

1 reference

2 September 2017

16 August 2004

1 reference

Journal of Lipid Research

2 September 2017

1 reference

2 September 2017

45

1 reference

2 September 2017

11

1 reference

2 September 2017

2000-2007

1 reference

Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis

2 September 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Sterol 14 alpha-demethylase and its inhibition: structural considerations on interaction of azole antifungal agents with lanosterol 14 alpha-demethylase (P-450(14DM)) of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Active efflux by multidrug transporters as one of the strategies to evade chemotherapy and novel practical implications of yeast pleiotropic drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Escherichia coli flavodoxin sepharose as an affinity resin for cytochromes P450 and use to identify a putative cytochrome P450c17/3beta-hydroxysteroid dehydrogenase interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400239-JLR200

10.1194/JLR.M400239-JLR200

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

15314102