(Q38337811)

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A solution NMR study of the interactions of oligomannosides and the anti-HIV-1 2G12 antibody reveals distinct binding modes for branched ligands.

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20 January 2020

A solution NMR study of the interactions of oligomannosides and the anti-HIV-1 2G12 antibody reveals distinct binding modes for branched ligands (English)

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20 January 2020

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20 January 2020

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20 January 2020

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20 January 2020

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Pedro M Enríquez-Navas

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20 January 2020

Soledad Penadés

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20 January 2020

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5 January 2011

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20 January 2020

Chemistry—A European Journal

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20 January 2020

17

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20 January 2020

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20 January 2020

1547-1560

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20 January 2020

The discovery of HIV as the cause of AIDS.

1 reference

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1 reference

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1 reference

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21 January 2018

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Covalent display of oligosaccharide arrays in microtiter plates

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

In pursuit of carbohydrate-based HIV vaccines, part 2: The total synthesis of high-mannose-type gp120 fragments--evaluation of strategies directed to maximal convergence

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

In pursuit of carbohydrate-based HIV vaccines, part 1: The total synthesis of hybrid-type gp120 fragments

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Carbohydrate microarrays as tools in HIV glycobiology

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Targeting FOXO kills two birds with one stone

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Toward a carbohydrate-based HIV-1 vaccine: synthesis and immunological studies of oligomannose-containing glycoconjugates

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Gold manno-glyconanoparticles: multivalent systems to block HIV-1 gp120 binding to the lectin DC-SIGN.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Complete relaxation and conformational exchange matrix (CORCEMA) analysis of intermolecular saturation transfer effects in reversibly forming ligand-receptor complexes

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

The effect of relaxation on the epitope mapping by saturation transfer difference NMR.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

NMR-based characterization of phenothiazines as a RNA binding scaffold

1 reference

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21 January 2018

NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Theory and applications of NMR-based screening in pharmaceutical research

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Novel template-assembled oligosaccharide clusters as epitope mimics for HIV-neutralizing antibody 2G12. Design, synthesis, and antibody binding study

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Complete relaxation and conformational exchange matrix (CORCEMA) analysis of NOESY spectra of interacting systems; two-dimensional transferred NOESY.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Inhibition of HIV fusion with multivalent gold nanoparticles

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002519

21 January 2018

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

1 reference

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21 January 2018

Rapid and accurate calculation of protein 1H, 13C and 15N chemical shifts

1 reference

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21 January 2018

Absorption-mode two-dimensional NMR spectra recorded using pulsed field gradients

1 reference

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21 January 2018

Identifiers

10.1002/CHEM.201002519

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268157%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21268157%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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