(Q38339368)

2 September 2017

title

Novel mechanism of inhibition of HIV-1 reverse transcriptase by a new non-nucleoside analog, KM-1. (English)

1 reference

2 September 2017

Louise Z Wang

1

1 reference

2 September 2017

George L Kenyon

series ordinal

2

1 reference

2 September 2017

Kenneth A Johnson

series ordinal

3

1 reference

2 September 2017

language of work or name

English

0 references

publication date

1 July 2004

1 reference

Journal of Biological Chemistry

2 September 2017

published in

1 reference

2 September 2017

volume

279

1 reference

2 September 2017

issue

37

1 reference

2 September 2017

page(s)

38424-38432

1 reference

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Safety, efficacy and development of resistance under the new protease inhibitor lopinavir/ritonavir: 48-week results

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Decreased frequencies of virus-specific T helper type 1 cells during interferon alpha plus ribavirin treatment in HIV-hepatitis C virus co-infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

A review of HIV-1 resistance to the nucleoside and nucleotide inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

HIV-1-specific RT inhibitors: highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Analysis of HIV-2 RT mutants provides evidence that resistance of HIV-1 RT and HIV-2 RT to nucleoside analogs involves a repositioning of the template-primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

The accuracy of reverse transcriptase from HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Update on HIV resistance and resistance testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

A novel mechanism for inhibition of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Purification and characterization of HIV-1 reverse transcriptase having a 1:1 ratio of p66 and p51 subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

A specific mechanism of nonspecific inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Lead discovery using molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406241200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406241200

1 reference

2 September 2017

1 reference