(Q38340063)

English

Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

0 references

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Frédéric Bost

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Jean-François Tanti

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

V Corcelle

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

T Grémeaux

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

K Laurent

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

A Waget

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

G Pagès

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

B Binétruy

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Y Le Marchand-Brustel

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

R Burcelin

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

15 October 2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

54

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

180-189

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-010-1944-0

0 references

Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1944-0

21 January 2018

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-ing up inflammation in fat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinases, inhibitory-kappaB kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ER stress and lipogenesis: a slippery slope toward hepatic steatosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role for ERK2 mitogen-activated protein kinase in placental development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity, Inflammation, and Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic lipids and organ function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF in LPS-stimulated macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet--induced obesity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global and societal implications of the diabetes epidemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new concept of adipose tissue function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin and energy expenditure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinases in the immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normalization of obesity-associated insulin resistance through immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute stimulation of glucose metabolism in mice by leptin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of MAPKs in adipocyte differentiation and obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of tumor necrosis factor-alpha-mediated plasminogen activator inhibitor-1 expression in adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20953578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-010-1944-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20953578%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38340063&oldid=1538937253"