(Q38345567)

2 September 2017

1 reference

title

From housekeeper to microsurgeon: the diagnostic and therapeutic potential of ribonucleases (English)

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2 September 2017

Schein CH

1

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PubMed ID

9181574

2 September 2017

language of work or name

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1 June 1997

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2 September 2017

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2 September 2017

15

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2 September 2017

6

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2 September 2017

529-536

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https://scigraph.springernature.com/pub.10.1038/nbt0697-529

2 September 2017

0 references

cites work

Enhanced expression of the eosinophil-derived neurotoxin ribonuclease (RNS2) gene requires interaction between the promoter and intron

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

A structural basis of the interactions between leucine-rich repeats and protein ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Purification and characterization of human brain ribonuclease inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Stoichiometry of 2',5'-oligoadenylate-induced dimerization of ribonuclease L. A sedimentation equilibrium study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Cloning and characterization of a RNAse L inhibitor. A new component of the interferon-regulated 2-5A pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Deletions at the C-terminus of interferon gamma reduce RNA binding and activation of double-stranded-RNA cleavage by bovine seminal ribonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Effect of interferon-gamma on complement gene expression in different cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

c-fos mRNA expression in macrophages is downregulated by interferon-gamma at the posttranscriptional level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Self-incompatibility (S) alleles of the Rosaceae encode members of a distinct class of the T2/S ribonuclease superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Differential effects of non-selective and selective phosphodiesterase inhibitors on human eosinophil functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

A neuroprotective compound, aurin tricarboxylic acid, stimulates the tyrosine phosphorylation cascade in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Inhibition of HIV-1 replication and activation of RNase L by phosphorothioate/phosphodiester 2',5'-oligoadenylate derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Mode of action of the anti-AIDS compound poly(I).poly(C12U) (Ampligen): activator of 2',5'-oligoadenylate synthetase and double-stranded RNA-dependent kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Large-scale preparation of a ribonuclease from Rana catesbeiana (bullfrog) oocytes and characterization of its specific cytotoxic activity against tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

N- and O-linked keratan sulfate on the hyaluronan binding region of aggrecan from mature and immature bovine cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Pseudogenes in ribonuclease evolution: a source of new biomacromolecular function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

The role of non-catalytic binding subsites in the endonuclease activity of bovine pancreatic ribonuclease A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

X-ray crystallographic structure of recombinant eosinophil-derived neurotoxin at 1.83 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Solution structure of bovine angiogenin by 1H nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Role of the N terminus in RNase A homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Site-directed mutagenesis of the base recognition loop of ribonuclease from Bacillus intermedius (binase).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Copurification of E. coli RNAase E and PNPase: evidence for a specific association between two enzymes important in RNA processing and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Nevirapine alters the cleavage specificity of ribonuclease H of human immunodeficiency virus 1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Epidermal growth factor receptor-dependent cytotoxic effect by an EGF-ribonuclease conjugate on human cancer cell lines--a trial for less immunogenic chimeric toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Angiogenin single-chain immunofusions: influence of peptide linkers and spacers between fusion protein domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Fusion with an RNA binding domain to confer target RNA specificity to an RNase: design and engineering of Tat-RNase H that specifically recognizes and cleaves HIV-1 RNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Therapeutic applications of ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Hammerhead ribozyme engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Sequence-specific cleavage of RNA by a hybrid ribonuclease H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Comparative analysis of ribonuclease P RNA using gene sequences from natural microbial populations reveals tertiary structural elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

The Ribonuclease P Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

A retrotransposon-like sequence linked to the S-locus of Nicotiana alata is expressed in styles in response to touch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Isolation and characterization of a 30 kDa protein with antifungal activity from leaves of Engelmannia pinnatifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

A hybrid protein kinase-RNase in an interferon-induced pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Mechanism of Ribonuclease Cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

Molecular evolution of genes encoding ribonucleases in ruminant species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Specific endonucleolytic cleavages of mouse albumin mRNA and their modulation during liver development

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Nature and possible origin of Human Serum ribonuclease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Hepatic Nucleases. Extrahepatic Origin and Association of Neutral Liver Ribonuclease with Lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Mammary origin of rat milk ribonuclease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Coupling between mRNA synthesis and mRNA stability in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

RNase E autoregulates its synthesis by controlling the degradation rate of its own mRNA in Escherichia coli: unusual sensitivity of the rne transcript to RNase E activity.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Identification of the cis-elements mediating the autogenous control of ribosomal protein L2 mRNA stability in yeast.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

'Holy' proteins. I: Ribonuclease inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The yeast RNA1 protein, necessary for RNA processing, is homologous to the human ribonuclease/angiogenin inhibitor (RAI)

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

High-resolution analysis of gro alpha mRNA poly(A) shortening: regulation by interleukin-1 beta

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Tumor-suppressor genes: news about the interferon connection

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Interferon-γ activates the cleavage of double-stranded RNA by bovine seminal ribonuclease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Posttranscriptional regulation of interferon mRNA levels in peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Interferon-gamma downregulates CFTR gene expression in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A novel fluorogenic substrate for ribonucleases. Synthesis and enzymatic characterization

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Toxicity of an antitumor ribonuclease to Purkinje neurons.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The major birch pollen allergen, Bet v 1, shows ribonuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Isolation and characterization of cDNAs encoding xylogenesis-associated and wounding-induced ribonucleases in Zinnia elegans.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Bean ribonuclease-like pathogenesis-related protein genes (Ypr10) display complex patterns of developmental, dark-induced and exogenous-stimulus-dependent expression.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Poly (C) avid ribonuclease estimation in patients with solid tumors. A critical evaluation

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Virus-induced cell death in plants expressing the mammalian 2',5' oligoadenylate system

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A 2',5'-oligoadenylate analogue inhibits murine hepatitis virus strain 3 (MHV-3) replication in vitro but does not reduce MHV-3-related mortality or induction of procoagulant activity in susceptible mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The DNA sequences of the human and hamster secretory ribonucleases determined with the polymerase chain reaction (PCR)

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Eosinophil cationic protein and eosinophil-derived neurotoxin. Evolution of novel function in a primate ribonuclease gene family

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A human RNase E-like activity that cleaves RNA sequences involved in mRNA stability control

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A heterodimeric nuclear protein complex binds two palindromic sequences in the proximal enhancer of the human erbB-2 gene

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Clavin, a type-1 ribosome-inactivating protein from Aspergillus clavatus IFO 8605. cDNA isolation, heterologous expression, biochemical and biological characterization of the recombinant protein.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The conformation of the sarcin/ricin loop from 28S ribosomal RNA

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Substrate specificity of monomeric and dimeric alpha-sarcin

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Determination by systematic deletion of the amino acids essential for catalysis by ricin A chain

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A protein complex mediating mRNA degradation in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The role of posttranscriptional modification in stabilization of transfer RNA from hyperthermophiles

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

A novel method for the determination of post-transcriptional modification in RNA by mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Hybridization specificity, enzymatic activity and biological (Ha-ras) activity of oligonucleotides containing 2,4-dideoxy-beta-D-erythro-hexopyranosyl nucleosides

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

The N-terminal domain of the rne gene product has RNase E activity and is non-overlapping with the arginine-rich RNA-binding site

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Immunotoxins: a clinical review of their use in the treatment of malignancies

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Kinetic study of the cytotoxic effect of alpha-sarcin, a ribosome inactivating protein from Aspergillus giganteus, on tumour cell lines: protein biosynthesis inhibition and cell binding

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Cleavage site selection by M1 RNA the catalytic subunit of Escherichia coli RNase P, is influenced by pH

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Functional interaction of heat shock protein GroEL with an RNase E-like activity in Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Resistance against multiple plant viruses in plants mediated by a double stranded-RNA specific ribonuclease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

RNase inhibition of human immunodeficiency virus infection of H9 cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Increased Serum Levels of Eosinophil Cationic Protein and Eosinophil-derived Neurotoxin (protein X) in Vernal Keratoconjunctivitis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Immunohistochemical demonstration of ribonuclease and amylase in normal and neoplastic parotid glands

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1 reference

https://api.crossref.org/works/10.1038%2FNBT0697-529

7 January 2021

Identifiers

DOI

10.1038/NBT0697-529

1 reference

2 September 2017

1 reference

PubMed ID

9181574