(Q38350716)

2 September 2017

Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites (English)

1 reference

2 September 2017

0 references

Kumuda C Das

1

1 reference

PubMed ID

12959929

2 September 2017

Ravi Dashnamoorthy

series ordinal

2

1 reference

2 September 2017

5 September 2003

1 reference

American Journal of Physiology - Lung Cellular and Molecular Physiology

2 September 2017

1 reference

2 September 2017

286

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2 September 2017

1

1 reference

2 September 2017

L87-97

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Cell cycle checkpoint signaling through the ATM and ATR kinases

2 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Chromosomal instability and progressive loss of chromosomes in HeLa cells during adaptation to hyperoxic growth conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Chromosomal instability in an oxygen-tolerant variant of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Mutagenicity of metabolic oxygen radicals in mammalian cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Mutation of phosphoserine 389 affects p53 function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Growth arrest in A549 cells during hyperoxic stress is associated with decreased cyclin B1 and increased p21(Waf1/Cip1/Sdi1) levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

DNA damage and cell cycle checkpoints in hyperoxic lung injury: braking to facilitate repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Growth arrest in G1 protects against oxygen-induced DNA damage and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Ataxia-telangiectasia: is ATM a sensor of oxidative damage and stress?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

The Ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00203.2002

10.1152/AJPLUNG.00203.2002

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

12959929